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Descriptor English: Basigin
Descriptor Spanish: Basigina
Descriptor basigina
Entry term(s) antígeno CD147
antígenos CD147
emmprina
inductor de metaloproteinasas de matriz extracelular
inductor de metaloproteinasas de matriz extracelular (EMMPRIN)
proteína basigina
proteína emmprina
Scope note: Glucoproteínas transmembranarias de la superficie celular ampliamente distribuidas, caracterizadas por DOMINIOS DE INMUNOGLOBULINA extracelulares. Estimulan la síntesis de METALOPROTEINASAS DE LA MATRIZ y se encuentran en altas concentraciones en la superficie de NEOPLASIAS malignas donde pueden desempeñar una función como mediadores del comportamiento de la célula cancerosa.
Descriptor Portuguese: Basigina
Descriptor French: Antigènes CD147
Entry term(s): Antigen, CD147
Antigens, CD147
Basigin Protein
CD147 Antigen
CD147 Antigens
Emmprin
Emmprin Protein
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
Tree number(s): D12.776.395.550.045
D12.776.543.550.187
D23.050.285.040
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051926
Scope note: A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 136894-56-9
Public MeSH Note: 2018; see ANTIGENS, CD147 2006-2017; BASIGIN was indexed under ANTIGENS, CD 2005; under ANTIGENS, SURFACE and BLOOD PROTEINS 1990-2004; under MEMBRANE GLYCOPROTEINS 1993-2004; and under GLYCOPROTEINS 1990-1992
History Note: 2018 (1990)
DeCS ID: 51077
Unique ID: D051926
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/05/24
Basigin - Preferred
Concept UI M0177703
Scope note A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
Preferred term Basigin
Entry term(s) Antigen, CD147
Antigens, CD147
Basigin Protein
CD147 Antigen
CD147 Antigens
Emmprin
Emmprin Protein
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)



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