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Descriptor English: Macrolides
Descriptor Spanish: Macrólidos
Descriptor macrólidos
Entry term(s) macrólido
Scope note: Grupo de compuestos macrocíclicos con frecuencia glucosilados formados por la extensión en cadena de múltiples PROPIONATOS y ciclizados en una gran lactona con gran número de miembros (típicamente 12, 14, 16). Los macrólidos pertenecen a la clase de POLICÉTIDOS de productos naturales y muchos miembros exhiben propiedades ANTIBIÓTICAS.
Descriptor Portuguese: Macrolídeos
Descriptor French: Macrolides
Entry term(s): Macrolide
Tree number(s): D02.540.505
D02.540.576.500
D04.345.674.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018942
Scope note: A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 96
History Note: 96
DeCS ID: 32697
Unique ID: D018942
NLM Classification: QV 350
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2020/05/27
Macrolides - Preferred
Concept UI M0028311
Scope note A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Preferred term Macrolides
Entry term(s) Macrolide



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