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Descriptor English: Syndecans
Descriptor Spanish: Sindecanos
Descriptor sindecanos
Scope note: Familia de glicoproteínas transmembrana que contienen una corto dominio citoplasmático, un dominio transmembrana de extensión única, y un dominio extracelular con cadenas de HEPARINA SULFATO y CONDROITINA SULFATO. Los sindecanos interactúan con diversas PROTEÍNAS Y PÉPTIDOS DE SEÑALIZACIÓN INTERCELULAR y pueden desempeñar un papel en la modulación de la señalización celular durante el DESARROLLO EMBRIONARIO, oncogénesis y angiogénesis.
Descriptor Portuguese: Sindecanas
Descriptor French: Syndécanes
Entry term(s): Syndecan
Tree number(s): D09.400.430.890.847
D09.400.430.930.350.500
D12.776.395.550.847
D12.776.395.650.350.500
D12.776.543.550.847
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053667
Scope note: A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2007; SYNDECANS was indexed under MEMBRANE GLYCOPROTEINS and PROTEOGLYCANS 1989-2005
History Note: 2007(1989)
DeCS ID: 52327
Unique ID: D053667
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2010/06/25
Syndecans - Preferred
Concept UI M0164318
Scope note A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.
Preferred term Syndecans
Entry term(s) Syndecan



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