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Descriptor English: Tetraspanins
Descriptor Spanish: Tetraspaninas
Descriptor Portuguese: Tetraspaninas
Descriptor French: Tétraspanines
Entry term(s): Tetraspanin
Tree number(s): D12.776.543.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D059470
Scope note: A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Membrane Proteins (1997-2011)
Public MeSH Note: 2012
History Note: 2012
Related: MARVEL Domain-Containing Proteins MeSH
DeCS ID: 54638
Unique ID: D059470
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2020/05/27
Tetraspanins - Preferred
Concept UI M0550244
Scope note A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES.
Preferred term Tetraspanins
Entry term(s) Tetraspanin



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