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Descriptor English: Bosentan
Descriptor Spanish: Bosentán
Descriptor bosentán
Entry term(s) 4-t-butil-N-(6-(2-hidroxietoxi)-5-(2-metoxifenoxi)-2,2'-bipirimidin-4-il)bencenosulfonamida
Ro 47 0203
Ro 47-0203
Ro 470203
Ro-47-0203
Tracleer
bosentán anhidra
bosentán monohidrato
Scope note: Derivado de sulfonamida y pirimidina que actúa como antagonista doble de los receptores de la endotelina y se usa para tratar la HIPERTENSIÓN PULMONAR Y LA ESCLEROSIS SISTÉMICA.
Descriptor Portuguese: Bosentana
Descriptor French: Bosentan
Entry term(s): Bosentan anhydre
Bosentan monohydraté
Ro-47-0203
Tree number(s): D02.065.884.135
D02.886.590.700.143
D03.383.742.060
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077300
Scope note: A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antihypertensive Agents
Endothelin Receptor Antagonists
Registry Number: Q326023R30
CAS Type 1 Name: Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-
DeCS ID: 57600
Unique ID: D000077300
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Bosentan - Preferred
Concept UI M000640413
Preferred term Bosentan
Bosentan monohydraté - Narrower
Concept UI M000637175
Preferred term Bosentan monohydraté
Bosentan anhydre - Narrower
Concept UI M0585634
Preferred term Bosentan anhydre
Ro-47-0203 - Narrower
Concept UI M0228617
Preferred term Ro-47-0203



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