| Descriptor English: | Nicotinamide-Nucleotide Adenylyltransferase | ||||||
| Descriptor Spanish: |
Nicotinamida-Nucleótido Adenililtransferasa
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| Descriptor Portuguese: | Nicotinamida-Nucleotídeo Adenililtransferase | ||||||
| Descriptor French: | Nicotinamide nucleotide adenylyltransferase | ||||||
| Entry term(s): |
ATP NMN Adenylyltransferase ATP-NMN Adenylyltransferase Adenylyltransferase, ATP-NMN Adenylyltransferase, NMN Adenylyltransferase, Nicotinamide Mononucleotide Adenylyltransferase, Nicotinamide-Nucleotide Mononucleotide Adenylyltransferase, Nicotinamide NAD Pyrophosphorylase NMN Adenylyltransferase Nicotinamide Mononucleotide Adenylyltransferase Nicotinamide Nucleotide Adenylyltransferase Pyrophosphorylase, NAD |
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| Tree number(s): |
D08.811.913.696.445.600 D12.776.157.687.499 D12.776.660.720.499 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D009612 | ||||||
| Scope note: | An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.7.1 | ||||||
| CAS Type 1 Name: | ATP:nicotinamide-nucleotide adenylyltransferase | ||||||
| Previous Indexing: |
Adenosine Triphosphate (1966-1978) Nicotinamide Mononucleotide (1973-1978) Nucleotidyltransferases (1966-1978) Transferases (1966-1967) |
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| Public MeSH Note: | 98; see NMN ADENYLYLTRANSFERASE 1991-97; see NUCLEOTIDYLTRANSFERASES 1979-90 |
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| History Note: | 98(79) |
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| DeCS ID: | 9799 | ||||||
| Unique ID: | D009612 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1978/03/13 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Nicotinamide-Nucleotide Adenylyltransferase
- Preferred
| Concept UI |
M0014930 |
| Scope note | An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. |
| Preferred term | Nicotinamide-Nucleotide Adenylyltransferase |
| Entry term(s) |
ATP NMN Adenylyltransferase ATP-NMN Adenylyltransferase Adenylyltransferase, ATP-NMN Adenylyltransferase, NMN Adenylyltransferase, Nicotinamide Mononucleotide Adenylyltransferase, Nicotinamide-Nucleotide Mononucleotide Adenylyltransferase, Nicotinamide NAD Pyrophosphorylase NMN Adenylyltransferase Nicotinamide Mononucleotide Adenylyltransferase Nicotinamide Nucleotide Adenylyltransferase Pyrophosphorylase, NAD |
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