| Descriptor English: | Ataxia Telangiectasia Mutated Proteins | ||||||
| Descriptor Spanish: |
Proteínas de la Ataxia Telangiectasia Mutada
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| Descriptor Portuguese: | Proteínas Mutadas de Ataxia Telangiectasia | ||||||
| Descriptor French: | Protéines mutées dans l'ataxie-télangiectasie | ||||||
| Entry term(s): |
A T Protein A-T Protein AT Mutated Protein ATM Protein Mutated Protein, AT Protein, A-T Protein, AT Mutated |
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| Tree number(s): |
D08.811.913.696.620.682.700.097 D12.776.157.687.125 D12.776.476.563.097 D12.776.660.720.125 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064007 | ||||||
| Scope note: | A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Public MeSH Note: | 2014; was indexed under PROTEIN KINASES 1983-1992; PROTEIN-SERINE-THREONINE KINASES 1993-2013 |
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| History Note: | 2014 |
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| DeCS ID: | 55299 | ||||||
| Unique ID: | D064007 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Ataxia Telangiectasia Mutated Proteins
- Preferred
| Concept UI |
M0248389 |
| Scope note | A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control. |
| Preferred term | Ataxia Telangiectasia Mutated Proteins |
| Entry term(s) |
A T Protein A-T Protein AT Mutated Protein ATM Protein Mutated Protein, AT Protein, A-T Protein, AT Mutated |
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