Search
Descriptor English: Protamines
Descriptor Spanish: Protaminas
Descriptor protaminas
Entry term(s) protamina
sulfato de protamina
Scope note: Grupo de proteínas simples que por hidrólisis producen aminoácidos básicos y que se encuentran combinadas con los ácidos nucleicos en la esperma de peces. Las protaminas contienen muy pocos tipos de aminoácidos. El sulfato de protamina se combina con la heparina para formar un complejo estable inactivo y se utiliza en el tratamiento de sobredosis de heparina para neutralizar su acción anticoagulante. (Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Descriptor Portuguese: Protaminas
Descriptor French: Protamine
Tree number(s): D12.776.660.750
D12.776.664.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011479
Scope note: A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Annotation: heparin antag
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Pharm Action: Heparin Antagonists
DeCS ID: 23432
Unique ID: D011479
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Protamine - Preferred
Concept UI M0017844
Preferred term Protamine



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey