Search
Descriptor English: Promyelocytic Leukemia Protein
Descriptor Spanish: Proteína de la Leucemia Promielocítica
Descriptor Portuguese: Proteína da Leucemia Promielocítica
Descriptor French: Protéine de la leucémie promyélocytaire
Entry term(s): RNF71 Protein
TRIM19 Protein
Tree number(s): D12.776.624.776.654
D12.776.660.745
D12.776.930.713
D12.776.934.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071156
Scope note: A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Nuclear Proteins (2008-2016)
Transcription Factors (2008-2016)
Tumor Suppressor Proteins (2008-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56647
Unique ID: D000071156
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/26
Promyelocytic Leukemia Protein - Preferred
Concept UI M000613226
Scope note A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Preferred term Promyelocytic Leukemia Protein
Entry term(s) RNF71 Protein
TRIM19 Protein



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey