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Descriptor English: Inhibitor of Growth Protein 1
Descriptor Spanish: Proteína Inhibidora del Crecimiento 1
Descriptor proteína inhibidora del crecimiento 1
Entry term(s) protein ING-1
proteína ING1
proteína p33ING
Scope note: Proteína nuclear supresora de tumores que contiene un motivo DEDOS DE ZINC PHD carboxiterminal. Se expresa en diferentes isoformas en diversos tejidos e interacciona con la PROTEÍNA SUPRESORA DE TUMOR P53 para regular negativamente el crecimiento celular. La disminución de la expresión y los reordenamientos cromosómicos del gen ING1 se asocian a diferentes tipos de cáncer, incluidas las NEOPLASIAS DE CABEZA Y CUELLO.
Descriptor Portuguese: Proteína 1 Inibidora do Crescimento
Descriptor French: Protéine-1 d'inhibition de croissance
Entry term(s): ING 1 Protein
ING-1 Protein
ING1 Protein
p33ING Protein
Tree number(s): D12.644.360.368
D12.776.476.383
D12.776.624.776.503
D12.776.660.494
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000076023
Scope note: A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Intracellular Signaling Peptides and Proteins (2005-2017)
Nuclear Proteins (2005-2017)
Tumor Suppressor Proteins (2005-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57059
Unique ID: D000076023
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Inhibitor of Growth Protein 1 - Preferred
Concept UI M000631818
Scope note A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
Preferred term Inhibitor of Growth Protein 1
Entry term(s) ING 1 Protein
ING-1 Protein
ING1 Protein
p33ING Protein



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