DeCS

Descriptor English:

Proto-Oncogene Proteins c-rel

Descriptor Spanish:

Proteínas Proto-Oncogénicas c-rel

Spanish from Spain

Descriptor	proteínas protooncogénicas c-rel
Entry term(s)	p68(c-rel) proteínas c-rel proteínas de protooncogén c-rel
Scope note:	Proteínas celulares de unión al ADN codificadas por el gen rel (GENES REL). Se expresan predominantemente en las células hematopoyéticas y pueden desempeñar un papel en la diferenciación linfocitaria. Rel se combina frecuentemente con otras proteínas relacionadas (FN-KAPPA B, I-kappa B, relA) para formar heterodímeros que regulan la transcripción. La reordenación o hiperexpresión de c-rel puede producir tumorigénesis.

Descriptor Portuguese:

Proteínas Proto-Oncogênicas c-rel

Descriptor French:

Protéines proto-oncogènes c-rel

Entry term(s):

Protein, c-rel
Proteins, c-rel
Proto Oncogene Products c rel
Proto Oncogene Protein c rel
Proto Oncogene Proteins c rel
Proto Oncogene Proteins rel
Proto-Oncogene Products c-rel
Proto-Oncogene Protein c-rel
Proto-Oncogene Proteins rel
Proto-Oncogene Proteins, rel
c rel Protein
c rel Proteins
c-rel Protein
c-rel Proteins
c-rel, Proto-Oncogene Products
c-rel, Proto-Oncogene Protein
c-rel, Proto-Oncogene Proteins
c-rel, p68
p68 c rel
p68 c-rel
p68(c-rel)
rel Proto Oncogene Product p68
rel Proto Oncogene Proteins
rel Proto-Oncogene Product p68
rel Proto-Oncogene Proteins

Tree number(s):

D12.776.260.682
D12.776.624.664.700.192
D12.776.660.767
D12.776.930.730

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D020569

Scope note:

Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Concept UI	M0328561
Scope note	Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.
Preferred term	Proto-Oncogene Proteins c-rel
Entry term(s)	Protein, c-rel Proteins, c-rel Proto Oncogene Products c rel Proto Oncogene Protein c rel Proto Oncogene Proteins c rel Proto Oncogene Proteins rel Proto-Oncogene Products c-rel Proto-Oncogene Protein c-rel Proto-Oncogene Proteins rel Proto-Oncogene Proteins, rel c rel Protein c rel Proteins c-rel Protein c-rel Proteins c-rel, Proto-Oncogene Products c-rel, Proto-Oncogene Protein c-rel, Proto-Oncogene Proteins c-rel, p68 p68 c rel p68 c-rel p68(c-rel) rel Proto Oncogene Product p68 rel Proto Oncogene Proteins rel Proto-Oncogene Product p68 rel Proto-Oncogene Proteins

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