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Descriptor English: Tumor Protein p73
Descriptor Spanish: Proteína Tumoral p73
Descriptor proteína tumoral p73
Entry term(s) p73 alfa
p73 beta
proteína TP73
proteína Tap73 humana
proteína Tap73, humana
proteína p73
proteína supresora de tumor p73
proteína supresora tumoral p73
Scope note: Homólogo de la PROTEÍNA SUPRESORA DE TUMORES P53 que codifica la isoforma transactivadora en toda su longitud y la isoforma truncada N-terminal (DeltaN). La detección de variantes de empalme e isoformas en el sistema nervioso (TELENCÉFALO humano, PLEXO COROIDEO, LÍQUIDO CEFALORRAQUÍDEO), el tejido embrionario, el CÁNCER DE MAMA humano y el CÁNCER DE OVARIO sugiere un papel en la diferenciación celular.
Descriptor Portuguese: Proteína Tumoral p73
Descriptor French: Protéine tumorale p73
Entry term(s): Human Tap73 Protein
Protein p73
Protein p73, Tumor
Protein, Human Tap73
Protein, TP73
Protein, p73
TP73 Protein
Tap73 Protein, Human
Tumor Suppressor Protein p73
p73 Protein
p73 alpha
p73 beta
p73, Protein
p73, Tumor Protein
p73-alpha
p73-beta
Tree number(s): D12.776.260.885
D12.776.624.776.820
D12.776.660.912
D12.776.930.969
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072160
Scope note: A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice variants and isoforms in the nervous system (human TELENCEPHALON, CHOROID PLEXUS; CEREBROSPINAL FLUID), embryonic tissue, human BREAST CANCER; OVARIAN CANCER, suggest roles in cellular differentiation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; TUMOR SUPPRESSOR PROTEIN p73 was indexed under GENES, TUMOR SUPPRESSOR 1997-2006 and under DNA-BINDING PROTEINS, NUCLEAR PROTEINS and TUMOR SUPPRESSOR PROTEINS 2007-2016
History Note: 2017 (1997)
DeCS ID: 56613
Unique ID: D000072160
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/07/05
Tumor Protein p73 - Preferred
Concept UI M0280871
Scope note A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice variants and isoforms in the nervous system (human TELENCEPHALON, CHOROID PLEXUS; CEREBROSPINAL FLUID), embryonic tissue, human BREAST CANCER; OVARIAN CANCER, suggest roles in cellular differentiation.
Preferred term Tumor Protein p73
Entry term(s) Human Tap73 Protein
Protein p73
Protein p73, Tumor
Protein, Human Tap73
Protein, p73
Tap73 Protein, Human
Tumor Suppressor Protein p73
p73 Protein
p73, Protein
p73, Tumor Protein
p73-alpha - Narrower
Concept UI M000617980
Preferred term p73-alpha
Entry term(s) p73 alpha
p73-beta - Narrower
Concept UI M000617981
Preferred term p73-beta
Entry term(s) p73 beta
TP73 Protein - Narrower
Concept UI M000618771
Preferred term TP73 Protein
Entry term(s) Protein, TP73



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