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Descriptor English: Host Cell Factor C1
Descriptor Spanish: Factor C1 de la Célula Huésped
Descriptor factor C1 de la célula anfitriona
Entry term(s) factor C1 de la célula hospedadora
factor C1 de la célula huésped
proteína HCFC1
Scope note: Coactivador transcripcional celular que contiene REPETICIONES KELCH N-terminales y DOMINIOS DE FIBRONECTINA TIPO III N- y C-terminales. Funciona como factor de transcripción de numerosos genes y en el ensamblaje de las PROTEÍNAS INMEDIATAS TEMPRANAS del VIRUS DEL HERPES SIMPLE. Las mutaciones en el gen HCFC1 se asocian a casos de RETRASO MENTAL LIGADO AL CROMOSOMA X.
Descriptor Portuguese: Fator C1 de Célula Hospedeira
Descriptor French: Facteur de prolifération cellulaire HCF
Entry term(s): C1 Host Cell Factor
Cell Proliferation Factor HCF
HCFC1 Protein
Tree number(s): D12.776.660.478
D12.776.930.325
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051863
Scope note: A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; HOST CELL FACTOR C1 was indexed under TRANSCRIPTION FACTORS 1995-2005
History Note: 2006(1995)
DeCS ID: 51188
Unique ID: D051863
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27
Host Cell Factor C1 - Preferred
Concept UI M0241725
Scope note A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
Preferred term Host Cell Factor C1
Entry term(s) C1 Host Cell Factor
Cell Proliferation Factor HCF
HCFC1 Protein



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