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Descriptor English: WT1 Proteins
Descriptor Spanish: Proteínas WT1
Descriptor proteínas WT1
Scope note: Isoformas codificadas por el gen supresor del tumor de Wilms WT1 (GENES DEL TUMOR DE WILMS) producidas por empalme alternativo. Se trata de factores de transcripción dedos de zinc involucrados tanto en la transactivación como en la represión, y son fundamentales para el normal desarrollo y funcionamiento del aparato genitourinario.
Descriptor Portuguese: Proteínas WT1
Descriptor French: Protéines WT1
Entry term(s): Gene Product, WT1
Protein, WT1
Proteins, WT1
WT1 Gene Product
WT1 Protein
Tree number(s): D12.776.624.776.960
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025721
Scope note: Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1991-2001)
Transcription Factors (1991-2001)
Public MeSH Note: 2002; WT1 PROTEIN was indexed as DNA-BINDING PROTEINS and TRANSCRIPTION FACTORS 1991-2001
History Note: 2002; for WT1 PROTEIN use WT1 PROTEINS (NM) 1991-2001
Related: Genes, Wilms Tumor MeSH
Wilms Tumor MeSH
DeCS ID: 36229
Unique ID: D025721
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2005/06/30
WT1 Proteins - Preferred
Concept UI M0193890
Scope note Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
Preferred term WT1 Proteins
Entry term(s) Gene Product, WT1
Protein, WT1
Proteins, WT1
WT1 Gene Product
WT1 Protein



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