| Descriptor English: | PTEN Phosphohydrolase | ||||
| Descriptor Spanish: |
Fosfohidrolasa PTEN
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| Descriptor Portuguese: | PTEN Fosfo-Hidrolase | ||||
| Descriptor French: | Phosphohydrolase PTEN | ||||
| Entry term(s): |
MMAC1 Protein Mutated In Multiple Advanced Cancers 1 Protein PTEN Phosphatase PTEN Protein PTEN Protein Phosphatase Phosphatase and Tensin Homologue on Chromosome Ten Protein Phosphatase, PTEN Phosphatase, PTEN Protein Phosphohydrolase, PTEN Protein Phosphatase, PTEN |
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| Tree number(s): |
D08.811.277.352.650.850 D12.776.476.590 D12.776.624.776.695 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051059 | ||||
| Scope note: | A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.1.3.67 | ||||
| Public MeSH Note: | 2006; PTEN PROTEIN was indexed under PROTEIN-TYROSINE-PHOSPHATASES 1997-1998, under TUMOR SUPPRESSOR PROTEINS 1997-2005, & under PHOSPHORIC MONOESTER HYDROLASES 1999-2005 |
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| History Note: | 2006(1997) |
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| DeCS ID: | 50580 | ||||
| Unique ID: | D051059 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 | ||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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PTEN Phosphohydrolase
- Preferred
| Concept UI |
M0479128 |
| Scope note | A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION. |
| Preferred term | PTEN Phosphohydrolase |
| Entry term(s) |
MMAC1 Protein Mutated In Multiple Advanced Cancers 1 Protein PTEN Phosphatase PTEN Protein PTEN Protein Phosphatase Phosphatase and Tensin Homologue on Chromosome Ten Protein Phosphatase, PTEN Phosphatase, PTEN Protein Phosphohydrolase, PTEN Protein Phosphatase, PTEN |
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