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Descriptor English: Complement C1 Inhibitor Protein
Descriptor Spanish: Proteína Inhibidora del Complemento C1
Descriptor Portuguese: Proteína Inibidora do Complemento C1
Descriptor French: C1 Inhibiteur
Entry term(s): C1 Esterase Inhibitor
C1 INH Protein
C1 Inhibitor Protein
C1-INH Protein
C1-Inhibitor Protein
Complement C1-Inhibitor Protein
Esterase Inhibitor, C1
G1, Serpin
Plasma Protease C1 Inhibitor
SERPING1
Serpin Family G Member 1
Serpin G1
Tree number(s): D12.644.861.140.500
D12.776.124.486.274.920.250.500
D12.776.395.320
D12.776.872.140.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050718
Scope note: An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Annotation: do not confuse with COMPLEMENT C1 INACTIVATOR PROTEINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Hereditary Angioedema Types I and II
Pharm Action: Complement Inactivating Agents
Previous Indexing: Complement C1 Inactivator Proteins (1970-2005)
Public MeSH Note: 2006; for C1 ESTERASE INHIBITOR see COMPLEMENT C1 INACTIVATOR PROTEINS
History Note: 2006; for C1 ESTERASE INHIBITOR use COMPLEMENT C1 INACTIVATOR PROTEINS
Entry Version: C 1 INH
DeCS ID: 50836
Unique ID: D050718
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/02/27
Complement C1 Inhibitor Protein - Preferred
Concept UI M0476632
Scope note An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Preferred term Complement C1 Inhibitor Protein
Entry term(s) C1 Esterase Inhibitor
C1 INH Protein
C1 Inhibitor Protein
C1-INH Protein
C1-Inhibitor Protein
Complement C1-Inhibitor Protein
Esterase Inhibitor, C1
G1, Serpin
Plasma Protease C1 Inhibitor
SERPING1
Serpin Family G Member 1
Serpin G1



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