| Descriptor English: | Imatinib Mesylate | ||||||
| Descriptor Spanish: |
Mesilato de Imatinib
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| Descriptor Portuguese: | Mesilato de Imatinib | ||||||
| Descriptor French: | Mésilate d'imatinib | ||||||
| Entry term(s): |
Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide CGP 57148 CGP-57148 CGP57148 CGP57148B Gleevec Glivec Imatinib Imatinib Methanesulfonate Mesylate, Imatinib Methanesulfonate, Imatinib ST 1571 ST1571 STI 571 STI-571 STI571 |
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| Tree number(s): |
D02.065.277.456 D02.241.223.100.100.435 D02.455.426.559.389.127.085.465 D03.383.606.405 D03.383.742.349 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000068877 | ||||||
| Scope note: | A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antineoplastic Agents Protein Kinase Inhibitors |
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| Registry Number: | 8A1O1M485B | ||||||
| Public MeSH Note: | 2016; IMATINIB MESYLATE was indexed under BENZAMIDES, PIPERAZINES, and PYRIMIDINES 1996-2015 |
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| History Note: | 2016 (1996) |
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| DeCS ID: | 55873 | ||||||
| Unique ID: | D000068877 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2016/01/01 | ||||||
| Date of Entry: | 2015/07/09 | ||||||
| Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Imatinib Mesylate
- Preferred
STI571
- Narrower
Gleevec
- Narrower
ST 1571
- Narrower
CGP 57148
- Narrower
Imatinib
- Broader
| Concept UI |
M0391958 |
| Scope note | A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors. |
| Preferred term | Imatinib Mesylate |
| Entry term(s) |
Imatinib Methanesulfonate Mesylate, Imatinib Methanesulfonate, Imatinib |
| Concept UI |
M0368581 |
| Preferred term | STI571 |
| Entry term(s) |
STI 571 STI-571 |
| Concept UI |
M0392345 |
| Preferred term | Gleevec |
| Entry term(s) |
Glivec |
| Concept UI |
M0400371 |
| Preferred term | ST 1571 |
| Entry term(s) |
ST1571 |
| Concept UI |
M0256578 |
| Preferred term | CGP 57148 |
| Entry term(s) |
CGP-57148 CGP57148 CGP57148B |
| Concept UI |
M0424454 |
| Preferred term | Imatinib |
| Entry term(s) |
Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide |
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