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Descriptor English: Mannose-Binding Protein-Associated Serine Proteases
Descriptor Spanish: Serina Proteasas Asociadas a la Proteína de Unión a la Manosa
Descriptor Portuguese: Serina Proteases Associadas a Proteína de Ligação a Manose
Descriptor French: Mannose-Binding Protein-Associated Serine Proteases
Entry term(s): MASP
MASP Proteases
MASP Related Protein
MASP-Related Protein
MASPs
MBL Associated Serine Proteases
MBL-Associated Serine Proteases
MBP Associated Serine Protease
MBP Associated Serine Protease Related Protein
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein
Mannan Binding Lectin Serine Proteases
Mannan-Binding Lectin Serine Proteases
Mannose Binding Protein Associated Serine Protease
Mannose-Binding Protein-Associated Serine Protease
Proteases, MASP
Protein, MASP-Related
Serine Protease, MBP-Associated
Serine Proteases, MBL-Associated
Tree number(s): D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050606
Scope note: Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.4.21.-
Previous Indexing: Mannose-Binding Lectins (1992-2005)
Serine Endopeptidases (1992-2005)
Public MeSH Note: 2006; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES was indexed under SERINE ENDOPEPTIDASES 1994-2005
History Note: 2006 (1994)
DeCS ID: 50582
Unique ID: D050606
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/06/17
Mannose-Binding Protein-Associated Serine Proteases - Preferred
Concept UI M0233323
Scope note Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
Preferred term Mannose-Binding Protein-Associated Serine Proteases
Entry term(s) MASP
MASP Proteases
MASPs
MBL Associated Serine Proteases
MBL-Associated Serine Proteases
MBP Associated Serine Protease
MBP-Associated Serine Protease
Mannan Binding Lectin Serine Proteases
Mannan-Binding Lectin Serine Proteases
Mannose Binding Protein Associated Serine Protease
Mannose-Binding Protein-Associated Serine Protease
Proteases, MASP
Serine Protease, MBP-Associated
Serine Proteases, MBL-Associated
MASP-Related Protein - Related but not broader or narrower
Concept UI M0361077
Preferred term MASP-Related Protein
Entry term(s) MASP Related Protein
MBP Associated Serine Protease Related Protein
MBP-Associated Serine Protease-Related Protein
Protein, MASP-Related



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