| Descriptor English: | Subtilisins | ||||
| Descriptor Spanish: | 
                                Subtilisinas                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Subtilisinas | ||||
| Descriptor French: | Subtilisines | ||||
| Entry term(s): | 
                                    Alcalase Alcalase, Novo AprA Subtilisin AprA-Subtilisin Bacillus amyloliquefaciens Serine Protease Bacillus subtilis Alkaline Proteinase Carlsberg Subtilisin Maxatase Nagarse Novo Alcalase Profezim Protease VII Subtilisin 72 Subtilisin A Subtilisin BPN' Subtilisin Carlsberg Subtilisin DY Subtilisin E Subtilisin GX Subtilisin Novo Subtilisin, Carlsberg Subtilopeptidase A  | 
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| Tree number(s): | 
                                        D08.811.277.656.300.760.787 D08.811.277.656.959.350.787  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013381 | ||||
| Scope note: | A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.- | 
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| Annotation: | SUBTILISIN is available | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine  | 
                                            ||||
| Registry Number: | EC 3.4.21.- | ||||
| Previous Indexing: | 
                                                Peptide Peptidohydrolases (1966-1972) | 
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| Public MeSH Note: | 74 | 
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| History Note: | 74(73) | 
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| DeCS ID: | 23469 | ||||
| Unique ID: | D013381 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1974/01/01 | ||||
| Date of Entry: | 1999/01/01 | ||||
| Revision Date: | 2013/07/09 | 
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                                        CHEMICALS AND DRUGS
 
Enzymes and Coenzymes [D08]Enzymes and Coenzymes - 
                                    
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes 
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                        Subtilisins                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Bacillus amyloliquefaciens Serine Protease                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Bacillus subtilis Alkaline Proteinase                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Subtilisin BPN'                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Profezim                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Protease VII                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Subtilisin Carlsberg                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Subtilisin 72                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        AprA-Subtilisin                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Maxatase                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0020698 | 
                                
| Scope note | A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.- | 
| Preferred term | Subtilisins | 
| Concept UI | 
                                        
                                        M0020687 | 
                                
| Preferred term | Bacillus amyloliquefaciens Serine Protease | 
| Concept UI | 
                                        
                                        M0020688 | 
                                
| Preferred term | Bacillus subtilis Alkaline Proteinase | 
| Concept UI | 
                                        
                                        M0020694 | 
                                
| Preferred term | Subtilisin BPN' | 
| Entry term(s) | 
                                        
                                                                                            Nagarse                                                 Subtilisin E Subtilisin GX Subtilisin Novo  | 
                                
| Concept UI | 
                                        
                                        M0020691 | 
                                
| Preferred term | Profezim | 
| Concept UI | 
                                        
                                        M0020692 | 
                                
| Preferred term | Protease VII | 
| Concept UI | 
                                        
                                        M0020689 | 
                                
| Preferred term | Subtilisin Carlsberg | 
| Entry term(s) | 
                                        
                                                                                            Alcalase                                                 Alcalase, Novo Carlsberg Subtilisin Novo Alcalase Subtilisin A Subtilisin DY Subtilisin, Carlsberg Subtilopeptidase A  | 
                                
| Concept UI | 
                                        
                                        M0020693 | 
                                
| Preferred term | Subtilisin 72 | 
| Concept UI | 
                                        
                                        M0020686 | 
                                
| Preferred term | AprA-Subtilisin | 
| Entry term(s) | 
                                        
                                                                                            AprA Subtilisin                                                 | 
                                
| Concept UI | 
                                        
                                        M0020690 | 
                                
| Preferred term | Maxatase | 
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