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Descriptor English: Proprotein Convertase 2
Descriptor Spanish: Proproteína Convertasa 2
Descriptor Portuguese: Pró-Proteína Convertase 2
Descriptor French: Proprotein convertase 2
Entry term(s): Convertase 2, Prohormone
Convertase 2, Proinsulin
Convertase PC2, Neuroendocrine
Convertase PC2, Prohormone
Convertase, PC2 Prohormone
Endopeptidase PC2
Endoprotease, PC2
Neuroendocrine Convertase PC2
PC2 Endoprotease
PC2 Prohormone Convertase
PC2 Protein
PC2, Endopeptidase
Prohormone Convertase 2
Prohormone Convertase PC2
Prohormone Convertase, PC2
Proinsulin Convertase 2
Tree number(s): D08.811.277.656.300.760.646
D08.811.277.656.837.562
D08.811.277.656.959.350.646
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045706
Scope note: A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.94
Previous Indexing: Subtilisins (1991-2003)
Public MeSH Note: 2004; PC2 PROTEIN (now PROPROTEIN CONVERTASE 2) was indexed under SUBTILISINS 1991-2003
History Note: 2004; use PROPROTEIN CONVERTASE 2 (NM) 1991-2003
DeCS ID: 38170
Unique ID: D045706
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2009/07/06
Proprotein Convertase 2 - Preferred
Concept UI M0183722
Scope note A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.
Preferred term Proprotein Convertase 2
Entry term(s) Convertase 2, Prohormone
Convertase 2, Proinsulin
Convertase PC2, Neuroendocrine
Convertase PC2, Prohormone
Convertase, PC2 Prohormone
Endopeptidase PC2
Endoprotease, PC2
Neuroendocrine Convertase PC2
PC2 Endoprotease
PC2 Prohormone Convertase
PC2 Protein
PC2, Endopeptidase
Prohormone Convertase 2
Prohormone Convertase PC2
Prohormone Convertase, PC2
Proinsulin Convertase 2



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