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Descriptor English: Proprotein Convertase 5
Descriptor Spanish: Proproteína Convertasa 5
Descriptor Portuguese: Pró-Proteína Convertase 5
Descriptor French: Proprotein convertase 5
Entry term(s): Convertase 5, Proprotein
Convertase PC-6, Prohormone
Convertase PC5, Prohormone
Convertase, PC5 Prohormone
Convertase, PC5 Proprotein
Convertase, PC5A Proprotein
Convertase, PC5B Preprotein
Convertase, PC6A Proprotein
Convertase-6, Prohormone
Endoprotease PC6
Endoprotease, PC6
PC5 Prohormone Convertase
PC5 Proprotein Convertase
PC5 Protein
PC5A Proprotein Convertase
PC5B Preprotein Convertase
PC6 Endoprotease
PC6 Protein
PC6A Proprotein Convertase
Preprotein Convertase, PC5B
Prohormone Convertase 6
Prohormone Convertase PC 6
Prohormone Convertase PC-6
Prohormone Convertase PC5
Prohormone Convertase, PC5
Prohormone Convertase-6
Proprotein Convertase, PC5
Proprotein Convertase, PC5A
Proprotein Convertase, PC6A
SPC6
Tree number(s): D08.811.277.656.300.760.648
D08.811.277.656.837.625
D08.811.277.656.959.350.648
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045702
Scope note: A serine endopeptidase found primarily in the EXTRACELLULAR MATRIX. It has specificity for cleavage of a variety of substrates including PRORENIN, pro-membrane type-1 matrix metalloproteinase, and NEURAL CELL ADHESION MOLECULE L1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.-
Previous Indexing: Serine Endopeptidases (1993-2003)
Subtilisins (1998-2003)
Public MeSH Note: 2004; PC5 PROPROTEIN CONVERTASE (now PREPROTEIN CONVERTASE 5) was indexed under SERINE ENDOPEPTIDASES 1993-1997 & SUBTILISINS 1998-2003
History Note: 2004; use PREPROTEIN CONVERTASE 5 (NM) 1993-2003; for PC6 ENDOPROTEASE use PREPROTEIN CONVERTASE 5 (NM) 1993-2003
DeCS ID: 38171
Unique ID: D045702
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/28
Proprotein Convertase 5 - Preferred
Concept UI M0219516
Scope note A serine endopeptidase found primarily in the EXTRACELLULAR MATRIX. It has specificity for cleavage of a variety of substrates including PRORENIN, pro-membrane type-1 matrix metalloproteinase, and NEURAL CELL ADHESION MOLECULE L1.
Preferred term Proprotein Convertase 5
Entry term(s) Convertase 5, Proprotein
Convertase PC-6, Prohormone
Convertase PC5, Prohormone
Convertase, PC5 Prohormone
Convertase, PC5 Proprotein
Convertase-6, Prohormone
Endoprotease PC6
Endoprotease, PC6
PC5 Prohormone Convertase
PC5 Proprotein Convertase
PC5 Protein
PC6 Endoprotease
PC6 Protein
Prohormone Convertase 6
Prohormone Convertase PC 6
Prohormone Convertase PC-6
Prohormone Convertase PC5
Prohormone Convertase, PC5
Prohormone Convertase-6
Proprotein Convertase, PC5
SPC6
PC5B Preprotein Convertase - Narrower
Concept UI M0447574
Preferred term PC5B Preprotein Convertase
Entry term(s) Convertase, PC5B Preprotein
Preprotein Convertase, PC5B
PC6A Proprotein Convertase - Narrower
Concept UI M0449071
Preferred term PC6A Proprotein Convertase
Entry term(s) Convertase, PC6A Proprotein
Proprotein Convertase, PC6A
PC5A Proprotein Convertase - Narrower
Concept UI M0447573
Preferred term PC5A Proprotein Convertase
Entry term(s) Convertase, PC5A Proprotein
Proprotein Convertase, PC5A



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