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Descriptor English: Fibrinolysin
Descriptor Spanish: Fibrinolisina
Descriptor fibrinolisina
Entry term(s) plasmina
Scope note: Producto de la lisis del plasminógeno (profibrinolisina) por los activadores del PLASMINÓGENO. Está compuesta por dos cadenas polipeptídicas, ligera (B) y pesada (A), con un peso molecular de 75,000. Es la principal enzima proteolítica implicada en la retracción del coágulo sanguíneo, o en la lisis de la fibrina y es desactivada rápidamente por las antiplasminas. EC 3.4.21.7.
Descriptor Portuguese: Fibrinolisina
Descriptor French: Fibrinolysine
Entry term(s): Fibrogammin
Glu Plasmin
Glu-Plasmin
Plasmin
Protease F
Thrombolysin
Tree number(s): D08.811.277.656.300.760.330
D08.811.277.656.959.350.330
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005341
Scope note: A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Fibrinolytic Agents
Registry Number: EC 3.4.21.7
Public MeSH Note: 2010, 1963-1992; see PLASMIN 1993-2009; for PLASMIN see FIBRINOLYSIN 1963-92
History Note: 2010, 1963-1992;
DeCS ID: 30897
Unique ID: D005341
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Fibrinolysin - Preferred
Concept UI M0008432
Scope note A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
Preferred term Fibrinolysin
Entry term(s) Glu Plasmin
Glu-Plasmin
Plasmin
Protease F
Fibrogammin - Narrower
Concept UI M0478247
Preferred term Fibrogammin
Thrombolysin - Narrower
Concept UI M0372964
Preferred term Thrombolysin



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