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Descriptor English: Factor IXa
Descriptor Spanish: Factor IXa
Descriptor factor IXa
Entry term(s) factor 9a
factor IX activado
factor de coagulación IXa
factor nueve A
Scope note: Forma activada del factor IX. Esta activación se realiza a través de la vía intrínseca por la acción del factor XIa y del calcio, o a través de la vía extrínseca, por la acción del factor VIIa, la tromboplastina y el calcio. El factor IXa sirve para activar el factor X para dar lugar al factor Xa, mediante escisión del enlace peptídico arginil-leucina del factor X.
Descriptor Portuguese: Fator IXa
Descriptor French: Facteur IXa
Entry term(s): Activated Factor IX
Blood Coagulation Factor IX, Activated
Coagulation Factor IXa
Factor 9A
Factor IX, Activated
Factor IXa, Coagulation
Factor Nine A
Tree number(s): D08.811.277.656.300.760.310
D08.811.277.656.959.350.310
D12.776.124.125.375.310
D23.119.375.310
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015949
Scope note: Activated form of factor IX. This activation can take place via the intrinsic pathway of blood coagulation by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Hemophilia B
Registry Number: EC 3.4.21.22
Previous Indexing: Factor IX (1975-1989)
Serine Proteinases (1988-1989)
Public MeSH Note: 90
History Note: 90
Related: Coagulants MeSH
DeCS ID: 24645
Unique ID: D015949
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/07/14
Revision Date: 2017/06/20
Factor IXa - Preferred
Concept UI M0024398
Scope note Activated form of factor IX. This activation can take place via the intrinsic pathway of blood coagulation by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.
Preferred term Factor IXa
Entry term(s) Activated Factor IX
Blood Coagulation Factor IX, Activated
Coagulation Factor IXa
Factor 9A
Factor IX, Activated
Factor IXa, Coagulation
Factor Nine A



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