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Descriptor English: Stromal Interaction Molecules
Descriptor Spanish: Moléculas de Interacción Estromal
Descriptor moléculas de interacción estromal
Entry term(s) molécula de interacción estromal
Scope note: Proteínas de unión al calcio asociadas a la membrana que se caracterizan por MOTIVOS EF HAND y un MOTIVO ALFA ESTÉRIL. Funcionan como sensores de las concentraciones de calcio del RETÍCULO ENDOPLÁSMICO y se translocan de este a la membrana plasmática para activar los CANALES DE CALCIO en respuesta a la reducción del calcio intracelular.
Descriptor Portuguese: Moléculas de Interação Estromal
Descriptor French: Molécules d'interaction stromale
Entry term(s): Interaction Molecule, Stromal
Molecule, Stromal Interaction
Stromal Interaction Molecule
Tree number(s): D12.776.157.125.806
D12.776.543.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071736
Scope note: Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Calcium Channels (1996-2016)
Membrane Proteins (1997-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56565
Unique ID: D000071736
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27
Stromal Interaction Molecules - Preferred
Concept UI M000615419
Scope note Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.
Preferred term Stromal Interaction Molecules
Entry term(s) Interaction Molecule, Stromal
Molecule, Stromal Interaction
Stromal Interaction Molecule



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