Descriptor English: | Urokinase-Type Plasminogen Activator | ||||||
Descriptor Spanish: |
Activador de Plasminógeno de Tipo Uroquinasa
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Descriptor Portuguese: | Ativador de Plasminogênio Tipo Uroquinase | ||||||
Descriptor French: | Activateur du plasminogène de type urokinase | ||||||
Entry term(s): |
Abbokinase Kidney Plasminogen Activator Plasminogen Activator, Urokinase-Type Renokinase Single Chain Urokinase Type Plasminogen Activator Single-Chain Urokinase-Type Plasminogen Activator U Plasminogen Activator U-PA U-Plasminogen Activator Urinary Plasminogen Activator Urokinase Urokinase Type Plasminogen Activator |
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Tree number(s): |
D08.811.277.656.300.760.910 D08.811.277.656.959.350.910 D12.776.124.125.662.884 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014568 | ||||||
Scope note: | A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 3.4.21.73 | ||||||
Previous Indexing: |
Fibrinolytic Agents (1966-1974) |
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Public MeSH Note: | 2009; see URINARY PLASMINOGEN ACTIVATOR 2000-2008, see UROKINASE 1984-1999, see PEPTIDE PEPTIDOHYDROLASES 1975-1983, see FIBRINOLYTIC AGENTS 1966-1974, see STREPTODORNASE AND STREPTOKINASE 1963-1965; UROKINASE-TYPE PLASMINOGEN ACTIVATOR was indexed under PLASMINOGEN ACTIVATORS & UROKINASE 1984-1999 |
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History Note: | 2009(1963) |
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DeCS ID: | 23502 | ||||||
Unique ID: | D014568 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1984/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Urokinase-Type Plasminogen Activator
- Preferred
Renokinase
- Narrower
Abbokinase
- Narrower
Kidney Plasminogen Activator
- Narrower
Single-Chain Urokinase-Type Plasminogen Activator
- Narrower
Concept UI |
M0022396 |
Scope note | A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES. |
Preferred term | Urokinase-Type Plasminogen Activator |
Entry term(s) |
Plasminogen Activator, Urokinase-Type U Plasminogen Activator U-PA U-Plasminogen Activator Urinary Plasminogen Activator Urokinase Urokinase Type Plasminogen Activator |
Concept UI |
M0333863 |
Preferred term | Renokinase |
Concept UI |
M0333864 |
Preferred term | Abbokinase |
Concept UI |
M0022397 |
Preferred term | Kidney Plasminogen Activator |
Concept UI |
M0022398 |
Preferred term | Single-Chain Urokinase-Type Plasminogen Activator |
Entry term(s) |
Single Chain Urokinase Type Plasminogen Activator |
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