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Descriptor English: Tumor Protein, Translationally-Controlled 1
Descriptor Spanish: Proteína Tumoral Controlada Traslacionalmente 1
Descriptor proteína tumoral controlada durante la transcripción 1
Entry term(s) factor liberador de histamina
factor liberador de histamina (dependiente de la IgE)
factor liberador de histamina dependiente de los linfocitos
proteína P23 del tumor ascítico de Ehrlich
proteína TPT1
proteína tumoral controlada durante la transcripción
Scope note: Proteína de elevada expresión en las células tumorales, codificada por el gen Tpt1. Interviene en diversas actividades celulares tales como la síntesis de proteínas, la unión al calcio, la estabilización de los MICROTÚBULOS, el crecimiento y la supervivencia celular. Además, se ha identificado Tpt1 como un gen diana directo de la proteína de supresión tumoral P53.
Descriptor Portuguese: Proteína Tumoral 1 Controlada por Tradução
Descriptor French: Protéine tumorale-1 contrôlée par la traduction
Entry term(s): Factor, Histamine Releasing
Histamine Releasing Factor
Histamine Releasing Factor, Lymphocyte Dependent
Histamine Releasing Factor, Lymphocyte-Dependent
Histamine-Releasing Factor (IgE-Dependent)
Protein P23, Ehrlich Ascites Tumor
Protein, TPT1
Protein, Translationally-Controlled Tumor
TPT1 Protein
Translationally Controlled Tumor Protein
Translationally-Controlled Tumor Protein
Tumor Protein, Translationally Controlled 1
Tumor Protein, Translationally-Controlled
Tree number(s): D12.644.360.963
D12.776.476.941
D12.776.624.720
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090324
Scope note: A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2022; TUMOR PROTEIN, TRANSLATIONALLY-CONTROLLED 1 was indexed under BIOMARKERS, TUMOR 1987-2021; under CALCIUM-BINDING PROTEINS 1997-2002; under GROWTH SUBSTANCES 1995-2002; under LYMPHOKINES 1985-2002; and under NEOPLASM PROTEINS 1994-2002
History Note: 2022 (1985)
DeCS ID: 59794
Unique ID: D000090324
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/01
Tumor Protein, Translationally-Controlled 1 - Preferred
Concept UI M0132475
Scope note A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression.
Preferred term Tumor Protein, Translationally-Controlled 1
Entry term(s) Factor, Histamine Releasing
Histamine Releasing Factor
Histamine Releasing Factor, Lymphocyte Dependent
Histamine Releasing Factor, Lymphocyte-Dependent
Histamine-Releasing Factor (IgE-Dependent)
Protein P23, Ehrlich Ascites Tumor
Protein, TPT1
Protein, Translationally-Controlled Tumor
TPT1 Protein
Translationally Controlled Tumor Protein
Translationally-Controlled Tumor Protein
Tumor Protein, Translationally Controlled 1
Tumor Protein, Translationally-Controlled



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