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Descriptor English: Guanylate Cyclase
Descriptor Spanish: Guanilato Ciclasa
Descriptor guanilato ciclasa
Entry term(s) guanil ciclasa
Scope note: Enzima que cataliza la conversión de GTP en 3',5'-GMP cíclico y pirofosfato. También actúa sobre ITP y dGTP. (Enzyme Nomenclature, 1992) EC 4.6.1.2.
Descriptor Portuguese: Guanilato Ciclase
Descriptor French: Guanylate cyclase
Entry term(s): Cyclase, Deoxyguanylate
Cyclase, Guanyl
Cyclase, Guanylate
Cyclase, Guanylyl
Cyclase, Inosinate
Deoxyguanylate Cyclase
Guanyl Cyclase
Guanylyl Cyclase
Inosinate Cyclase
Tree number(s): D08.811.520.650.600
D12.776.476.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006162
Scope note: An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.6.1.2
CAS Type 1 Name: GTP pyrophosphate-lyase (cyclizing)
Previous Indexing: Nucleotidyltransferases (1966-1972)
Public MeSH Note: 94; was GUANYL CYCLASE 1973-94
Online Note: use GUANYLATE CYCLASE to search GUANYL CYCLASE 1973-94
History Note: 94; was GUANYL CYCLASE 1973-94
DeCS ID: 6312
Unique ID: D006162
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/11/23
Guanylate Cyclase - Preferred
Concept UI M0009695
Scope note An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
Preferred term Guanylate Cyclase
Entry term(s) Cyclase, Deoxyguanylate
Cyclase, Guanyl
Cyclase, Guanylate
Cyclase, Guanylyl
Cyclase, Inosinate
Deoxyguanylate Cyclase
Guanyl Cyclase
Guanylyl Cyclase
Inosinate Cyclase



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