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Descriptor English: Inhibins
Descriptor Spanish: Inhibinas
Descriptor inhibinas
Scope note: Glicoproteínas que inhiben la secreción de la FSH hipofisaria. Las inhibinas son secretadas por las células de Sertoli testiculares, las células de la granulosa de los folículos ováricos, la placenta y otros tejidos. Las inhibinas y las ACTIVINAS modulan la secreción de FSH; ambos grupos pertenecen a la superfamilia del TGF-beta, como el FACTOR BETA TRANSFORMADOR DEL CRECIMIENTO. Las inhibinas son un heterodímero con enlaces disulfuro con una sola subunidad alfa que se une a una subunidad beta A o beta B para formar la inhibina A o la inhibina B, respectivamente.
Descriptor Portuguese: Inibinas
Descriptor French: Inhibines
Entry term(s): Female Inhibin
Female Inhibins
Inhibin
Inhibin F
Inhibin, Female
Inhibin, Ovarian
Inhibin, Testicular
Inhibin-F
Inhibins, Female
Inhibins, Testicular
Ovarian Inhibin
Testicular Inhibin
Testicular Inhibins
Tree number(s): D06.472.334.968
D06.472.699.337
D09.400.430.883
D12.644.548.387
D12.776.395.439
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007265
Scope note: Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 57285-09-3
CAS Type 1 Name: Inhibin
Previous Indexing: Proteins (1966-1982)
Testicular Hormones (1975-1982)
Public MeSH Note: 2002; see INHIBIN 1983-2001
History Note: 2002; (1983)
DeCS ID: 7440
Unique ID: D007265
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/05/11
Revision Date: 2006/07/05
Inhibins - Preferred
Concept UI M0011340
Scope note Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
Preferred term Inhibins
Entry term(s) Inhibin
Inhibins, Testicular - Narrower
Concept UI M0011343
Preferred term Inhibins, Testicular
Entry term(s) Inhibin, Testicular
Testicular Inhibin
Testicular Inhibins
Inhibins, Female - Narrower
Concept UI M0011339
Preferred term Inhibins, Female
Entry term(s) Female Inhibin
Female Inhibins
Inhibin F
Inhibin, Female
Inhibin, Ovarian
Inhibin-F
Ovarian Inhibin



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