ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT Investigative Techniques [E05] Investigative Techniques Genetic Techniques [E05.393] Genetic Techniques Cellular Reprogramming Techniques [E05.393.085] Cellular Reprogramming Techniques Chromatin Immunoprecipitation [E05.393.170] Chromatin Immunoprecipitation Chromosome Mapping [E05.393.183] Chromosome Mapping Cloning, Molecular [E05.393.220] Cloning, Molecular Cloning, Organism [E05.393.240] Cloning, Organism Contig Mapping [E05.393.260] Contig Mapping Crosses, Genetic [E05.393.281] Crosses, Genetic Cytogenetic Analysis [E05.393.285] Cytogenetic Analysis DNA Fingerprinting [E05.393.290] DNA Fingerprinting DNA Footprinting [E05.393.300] DNA Footprinting Gene Expression Profiling [E05.393.332] Gene Expression Profiling Gene Targeting [E05.393.335] Gene Targeting Gene Transfer Techniques [E05.393.350] Gene Transfer Techniques Genetic Association Studies [E05.393.385] Genetic Association Studies Genetic Engineering [E05.393.420] Genetic Engineering Genetic Testing [E05.393.435] Genetic Testing Genotyping Techniques [E05.393.442] Genotyping Techniques In Situ Nick-End Labeling [E05.393.475] In Situ Nick-End Labeling Molecular Diagnostic Techniques [E05.393.520] Molecular Diagnostic Techniques Molecular Epidemiology [E05.393.522] Molecular Epidemiology Molecular Typing [E05.393.542] Molecular Typing Mutagenicity Tests [E05.393.560] Mutagenicity Tests Nuclease Protection Assays [E05.393.600] Nuclease Protection Assays Nucleic Acid Amplification Techniques [E05.393.620] Nucleic Acid Amplification Techniques Nucleic Acid Denaturation [E05.393.640] Nucleic Acid Denaturation Nucleic Acid Hybridization [E05.393.661] Nucleic Acid Hybridization Branched DNA Signal Amplification Assay [E05.393.661.124] Branched DNA Signal Amplification Assay Comparative Genomic Hybridization [E05.393.661.187] Comparative Genomic Hybridization Heteroduplex Analysis [E05.393.661.250] Heteroduplex Analysis In Situ Hybridization [E05.393.661.475] In Situ Hybridization Oligonucleotide Array Sequence Analysis [E05.393.661.640] Oligonucleotide Array Sequence Analysis Subtractive Hybridization Techniques [E05.393.661.820] Subtractive Hybridization Techniques Optogenetics [E05.393.667] Optogenetics Pedigree [E05.393.673] Pedigree Restriction Mapping [E05.393.712] Restriction Mapping Reverse Genetics [E05.393.731] Reverse Genetics Sequence Alignment [E05.393.751] Sequence Alignment Sequence Analysis [E05.393.760] Sequence Analysis Viral Pseudotyping [E05.393.880] Viral Pseudotyping PHENOMENA AND PROCESSES Chemical Phenomena [G02] Chemical Phenomena Biochemical Phenomena [G02.111] Biochemical Phenomena Acid-Base Equilibrium [G02.111.007] Acid-Base Equilibrium Acylation [G02.111.012] Acylation Aerobiosis [G02.111.017] Aerobiosis Agglutination [G02.111.026] Agglutination Alkylation [G02.111.035] Alkylation Allosteric Regulation [G02.111.044] Allosteric Regulation Amination [G02.111.053] Amination Anaerobiosis [G02.111.062] Anaerobiosis Autotrophic Processes [G02.111.071] Autotrophic Processes Base Composition [G02.111.080] Base Composition Binding, Competitive [G02.111.084] Binding, Competitive Biocatalysis [G02.111.086] Biocatalysis Biomineralization [G02.111.092] Biomineralization Biosynthetic Pathways [G02.111.098] Biosynthetic Pathways Biotinylation [G02.111.109] Biotinylation Body Composition [G02.111.130] Body Composition Brain Chemistry [G02.111.150] Brain Chemistry Carbohydrate Metabolism [G02.111.158] Carbohydrate Metabolism Citric Acid Cycle [G02.111.165] Citric Acid Cycle Cyclization [G02.111.180] Cyclization Dealkylation [G02.111.188] Dealkylation Deamination [G02.111.192] Deamination Decarboxylation [G02.111.195] Decarboxylation DNA Cleavage [G02.111.210] DNA Cleavage DNA Methylation [G02.111.218] DNA Methylation DNA Repair [G02.111.222] DNA Repair DNA Replication [G02.111.225] DNA Replication Down-Regulation [G02.111.240] Down-Regulation Electron Transport [G02.111.248] Electron Transport Energy Transfer [G02.111.255] Energy Transfer Enzyme Activation [G02.111.263] Enzyme Activation Esterification [G02.111.270] Esterification Halogenation [G02.111.323] Halogenation Heterotrophic Processes [G02.111.375] Heterotrophic Processes Hydrogenation [G02.111.380] Hydrogenation Hydroxylation [G02.111.385] Hydroxylation Kinetics [G02.111.490] Kinetics Lipid Peroxidation [G02.111.515] Lipid Peroxidation Lipogenesis [G02.111.528] Lipogenesis Lipolysis [G02.111.534] Lipolysis Lipoylation [G02.111.540] Lipoylation Melanogenesis [G02.111.545] Melanogenesis Membrane Fluidity [G02.111.550] Membrane Fluidity Molecular Mimicry [G02.111.560] Molecular Mimicry Molecular Structure [G02.111.570] Molecular Structure Nitrogen Cycle [G02.111.587] Nitrogen Cycle Nitrosation [G02.111.595] Nitrosation Nucleic Acid Denaturation [G02.111.603] Nucleic Acid Denaturation Nucleic Acid Hybridization [G02.111.611] Nucleic Acid Hybridization Base Pairing [G02.111.611.500] Base Pairing Nucleic Acid Renaturation [G02.111.619] Nucleic Acid Renaturation Osmoregulation [G02.111.635] Osmoregulation Osmosis [G02.111.655] Osmosis Peptide Biosynthesis [G02.111.660] Peptide Biosynthesis Phosphorylation [G02.111.665] Phosphorylation Phototrophic Processes [G02.111.669] Phototrophic Processes Prenylation [G02.111.672] Prenylation Protein Aggregation, Pathological [G02.111.675] Protein Aggregation, Pathological Protein Binding [G02.111.679] Protein Binding Protein Folding [G02.111.688] Protein Folding Protein Modification, Translational [G02.111.691] Protein Modification, Translational Protein Multimerization [G02.111.694] Protein Multimerization Protein Stability [G02.111.700] Protein Stability Proteolysis [G02.111.720] Proteolysis Proteostasis [G02.111.730] Proteostasis RNA Cleavage [G02.111.740] RNA Cleavage RNA Folding [G02.111.750] RNA Folding RNA Processing, Post-Transcriptional [G02.111.760] RNA Processing, Post-Transcriptional RNA Replication [G02.111.770] RNA Replication RNA Stability [G02.111.780] RNA Stability Sequence Homology [G02.111.810] Sequence Homology Signal Transduction [G02.111.820] Signal Transduction Structure-Activity Relationship [G02.111.830] Structure-Activity Relationship Substrate Cycling [G02.111.833] Substrate Cycling Substrate Specificity [G02.111.835] Substrate Specificity Transcription, Genetic [G02.111.873] Transcription, Genetic Up-Regulation [G02.111.905] Up-Regulation

Nucleic Acid Hybridization - Preferred

Concept UI	M0015052
Scope note	Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Preferred term	Nucleic Acid Hybridization
Entry term(s)	Acid Hybridization, Nucleic Acid Hybridizations, Nucleic Hybridization, Nucleic Acid Hybridizations, Nucleic Acid Nucleic Acid Hybridizations

Genomic Hybridization - Broader

Concept UI	M0015053
Preferred term	Genomic Hybridization
Entry term(s)	Genomic Hybridizations Hybridization, Genomic Hybridizations, Genomic