| Descriptor English: | Complement Factor D | ||||||
| Descriptor Spanish: |
Factor D del Complemento
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| Descriptor Portuguese: | Fator D do Complemento | ||||||
| Descriptor French: | Facteur D du complément | ||||||
| Entry term(s): |
28 kDa Protein, Adipocyte Activator, C3 Convertase Adipsin C3 Convertase Activator C3 Proactivator Convertase C3PA Convertase C3PAse Complement D Component Complement Protein D Convertase Activator, C3 Convertase, C3 Proactivator Convertase, C3PA Convertase, Proactivator D Component of Complement Factor D Factor D, Complement Factor D, Properdin GBGase Proactivator Convertase Properdin Factor D Protein D, Complement |
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| Tree number(s): |
D08.811.277.300.450 D08.811.277.656.300.760.200 D08.811.277.656.959.350.200 D12.776.124.486.274.045.450 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011416 | ||||||
| Scope note: | A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE. |
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| Annotation: | see SCR for organism-specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Immunologic Factors |
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| Registry Number: | EC 3.4.21.46 | ||||||
| Previous Indexing: |
Enzyme Precursors (1966-1977) Properdin (1966-1977) Serum Globulins (1970-1977) |
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| Public MeSH Note: | 1999; see PROPERDIN FACTOR D 1991-1998, see COMPLEMENT ACTIVATING ENZYMES 1978-1990; ADIPSIN was indexed under SERINE ENDOPEPTIDASES 1987-2005 |
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| History Note: | 1999 (1978) |
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| DeCS ID: | 23520 | ||||||
| Unique ID: | D011416 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1977/05/20 | ||||||
| Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Complement Factor D
- Preferred
| Concept UI |
M0017753 |
| Scope note | A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE. |
| Preferred term | Complement Factor D |
| Entry term(s) |
28 kDa Protein, Adipocyte Activator, C3 Convertase Adipsin C3 Convertase Activator C3 Proactivator Convertase C3PA Convertase C3PAse Complement D Component Complement Protein D Convertase Activator, C3 Convertase, C3 Proactivator Convertase, C3PA Convertase, Proactivator D Component of Complement Factor D Factor D, Complement Factor D, Properdin GBGase Proactivator Convertase Properdin Factor D Protein D, Complement |
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