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Descriptor English: Proprotein Convertase 1
Descriptor Spanish: Proproteína Convertasa 1
Descriptor proproteína convertasa 1
Entry term(s) prohormona convertasa PC1
Scope note: Endopeptidasa dependiente del CALCIO con especificidad para la escisión en la ARGININA que está junto a residuos básicos pareados. Escinde diversas prohormonas, como la PROOPIOMELANOCORTINA, la PRORRENINA, las proencefalinas, la prodinorfina, la prosomatostatina y la PROINSULINA.
Descriptor Portuguese: Pró-Proteína Convertase 1
Descriptor French: Proprotein convertase 1
Entry term(s): Convertase neuroendocrine PC1
Endoprotéase PC1
Endoprotéase PC3
Prohormone convertase 1
Prohormone convertase 3
Prohormone convertase PC1
Prohormone convertase PC3
Proinsuline Convertase 1
Proprotéine Convertase SPC3
Proprotéine convertase 1
Tree number(s): D08.811.277.656.300.760.640
D08.811.277.656.837.500
D08.811.277.656.959.350.640
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045664
Scope note: A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.93
DeCS ID: 38169
Unique ID: D045664
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2009/07/06
Proprotein convertase 1 - Preferred
Concept UI M0103931
Preferred term Proprotein convertase 1
Entry term(s) Convertase neuroendocrine PC1
Endoprotéase PC1
Endoprotéase PC3
Prohormone convertase 1
Prohormone convertase 3
Prohormone convertase PC1
Prohormone convertase PC3
Proinsuline Convertase 1
Proprotéine Convertase SPC3
Proprotéine convertase 1



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