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Descriptor English: Myeloid Differentiation Factor 88
Descriptor Spanish: Factor 88 de Diferenciación Mieloide
Descriptor Portuguese: Fator 88 de Diferenciação Mieloide
Descriptor French: Facteur de différenciation myéloïde-88
Entry term(s): MyD88 Protein
TLR Signal Adaptor Protein MyD88
Toll Like Receptor Signal Adaptor Protein MyD88
Toll-Like Receptor Signal Adaptor Protein MyD88
Tree number(s): D12.644.360.024.311
D12.776.157.057.074
D12.776.476.024.390
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053594
Scope note: An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; MYELOID DIFFERENTIATION FACTOR 88 was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2006, under ANTIGENS, DIFFERENTIATION & RECEPTORS, IMMUNOLOGIC 2000-2006, & under PROTEINS 1990-1999
History Note: 2007(1990)
DeCS ID: 52313
Unique ID: D053594
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/03/30
Myeloid Differentiation Factor 88 - Preferred
Concept UI M0178953
Scope note An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
Preferred term Myeloid Differentiation Factor 88
Entry term(s) MyD88 Protein
TLR Signal Adaptor Protein MyD88
Toll Like Receptor Signal Adaptor Protein MyD88
Toll-Like Receptor Signal Adaptor Protein MyD88



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