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Descriptor English: A Kinase Anchor Proteins
Descriptor Spanish: Proteínas de Anclaje a la Quinasa A
Descriptor Portuguese: Proteínas de Ancoragem à Quinase A
Descriptor French: Protéines d'ancrage aux protéines kinases A
Entry term(s): A Kinase Anchoring Protein
A Kinase Anchoring Proteins
A-Kinase Anchor Proteins
A-Kinase Anchoring Protein
A-Kinase Anchoring Proteins
Anchor Proteins, A-Kinase
Anchoring Protein, A-Kinase
Protein Kinase A Anchor Proteins
Protein, A-Kinase Anchoring
Tree number(s): D12.644.360.024.065
D12.776.157.057.003
D12.776.476.024.069
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054758
Scope note: A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52783
Unique ID: D054758
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2020/01/16
A Kinase Anchor Proteins - Preferred
Concept UI M0507519
Scope note A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Preferred term A Kinase Anchor Proteins
Entry term(s) A Kinase Anchoring Protein
A Kinase Anchoring Proteins
A-Kinase Anchor Proteins
A-Kinase Anchoring Protein
A-Kinase Anchoring Proteins
Anchor Proteins, A-Kinase
Anchoring Protein, A-Kinase
Protein Kinase A Anchor Proteins
Protein, A-Kinase Anchoring



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