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Descriptor English: Rapamycin-Insensitive Companion of mTOR Protein
Descriptor Spanish: Proteína Asociada al mTOR Insensible a la Rapamicina
Descriptor proteína insensible a la rapamicina asociada a mTOR
Entry term(s) proteína RICTOR
Scope note: Subunidad proteica adaptadora del complejo MTORC-2. Funciona como componente estructural y es fosforilada por las PROTEÍNAS QUINASAS S6 RIBOSÓMICAS, integrando señales para el crecimiento y la proliferación celulares, especialmente durante el desarrollo embrionario.
Descriptor Portuguese: Proteína Companheira de mTOR Insensível à Rapamicina
Descriptor French: Compagnon de mTOR insensible à la rapamycine
Entry term(s): RICTOR Protein
Rapamycin Insensitive Companion of mTOR Protein
Tree number(s): D05.500.356.500
D08.811.913.696.620.682.700.931.750.500
D12.644.360.024.323
D12.776.157.057.156
D12.776.476.024.411
D12.776.476.563.931.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000076226
Scope note: An adaptor protein subunit of MTORC2 COMPLEX. It functions as a structural component and is phosphorylated by RIBOSOMAL PROTEIN S6 KINASES, integrating signals for cell growth and proliferation, especially during embryonic development.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Carrier Proteins (2004-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 56986
Unique ID: D000076226
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Rapamycin-Insensitive Companion of mTOR Protein - Preferred
Concept UI M000632476
Scope note An adaptor protein subunit of MTORC2 COMPLEX. It functions as a structural component and is phosphorylated by RIBOSOMAL PROTEIN S6 KINASES, integrating signals for cell growth and proliferation, especially during embryonic development.
Preferred term Rapamycin-Insensitive Companion of mTOR Protein
Entry term(s) RICTOR Protein
Rapamycin Insensitive Companion of mTOR Protein



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