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Descriptor English: Regulatory-Associated Protein of mTOR
Descriptor Spanish: Proteína Reguladora Asociada a mTOR
Descriptor Portuguese: Proteína Regulatória Associada a mTOR
Descriptor French: Protéine de régulation associée à mTOR
Entry term(s): RAPTOR Protein
RPTOR Protein
Regulatory Associated Protein of mTOR
mTOR Regulatory-Associated Protein
Tree number(s): D05.500.337.500
D08.811.913.696.620.682.700.931.500.500
D12.644.360.024.324
D12.776.157.057.157
D12.776.476.024.419
D12.776.476.925.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000076223
Scope note: An adaptor protein component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 that forms stoichiometric complexes with TOR KINASES, which it negatively regulates. It functions as a positive regulator of RIBOSOMAL PROTEIN S6 KINASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Adaptor Proteins, Signal Transducing (2011-2017)
Proteins (2002-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 56984
Unique ID: D000076223
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Regulatory-Associated Protein of mTOR - Preferred
Concept UI M000632473
Scope note An adaptor protein component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 that forms stoichiometric complexes with TOR KINASES, which it negatively regulates. It functions as a positive regulator of RIBOSOMAL PROTEIN S6 KINASES.
Preferred term Regulatory-Associated Protein of mTOR
Entry term(s) RAPTOR Protein
RPTOR Protein
Regulatory Associated Protein of mTOR
mTOR Regulatory-Associated Protein



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