| Descriptor English: | Homer Scaffolding Proteins | ||||||
| Descriptor Spanish: |
Proteínas de Andamiaje Homer
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| Descriptor Portuguese: | Proteínas de Arcabouço Homer | ||||||
| Descriptor French: | Protéines d'échafaudage Homer | ||||||
| Entry term(s): |
Homer 1 Homer 1 Proteins Homer 1C Homer 1C Proteins Homer 1a Homer 2 Homer 2 Proteins Homer 3 Homer 3 Proteins Homer Protein Homer Proteins Proteins, Homer Proteins, Homer 1 Proteins, Homer 1C Proteins, Homer 2 Proteins, Homer 3 Proteins, Homer Scaffolding Scaffolding Proteins, Homer |
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| Tree number(s): |
D12.776.476.024.381 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072233 | ||||||
| Scope note: | Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2017; HOMER PROTEIN was indexed under NEUROPEPTIDES 1997-2004, and under CARRIER PROTEINS 2005-2016 |
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| History Note: | 2017 (1997) |
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| DeCS ID: | 56636 | ||||||
| Unique ID: | D000072233 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/11 | ||||||
| Revision Date: | 2016/07/08 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Homer Scaffolding Proteins
- Preferred
Homer 1C
- Narrower
Homer 3
- Narrower
Homer 2
- Narrower
Homer 1
- Narrower
Homer 1a
- Narrower
| Concept UI |
M0274049 |
| Scope note | Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome. |
| Preferred term | Homer Scaffolding Proteins |
| Entry term(s) |
Homer Protein Homer Proteins Proteins, Homer Proteins, Homer Scaffolding Scaffolding Proteins, Homer |
| Concept UI |
M000618188 |
| Preferred term | Homer 1C |
| Entry term(s) |
Homer 1C Proteins Proteins, Homer 1C |
| Concept UI |
M000618191 |
| Preferred term | Homer 3 |
| Entry term(s) |
Homer 3 Proteins Proteins, Homer 3 |
| Concept UI |
M000618190 |
| Preferred term | Homer 2 |
| Entry term(s) |
Homer 2 Proteins Proteins, Homer 2 |
| Concept UI |
M000618187 |
| Preferred term | Homer 1 |
| Concept UI |
M000618189 |
| Preferred term | Homer 1a |
| Entry term(s) |
Homer 1 Proteins Proteins, Homer 1 |
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