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Descriptor English: Protein Inhibitors of Activated STAT
Descriptor Spanish: Proteínas Inhibidoras de STAT Activados
Descriptor Portuguese: Proteínas Inibidoras de STAT Ativados
Descriptor French: Inhibiteurs de STAT activés
Entry term(s): PIAS Proteins
PIAS1 Protein
PIAS1 Protein Inhibitor of Activated STAT
PIAS2 Protein Inhibitor of Activated STAT
PIAS3 Protein Inhibitor of Activated STAT
PIAS4 Protein Inhibitor of Activated STAT
Tree number(s): D12.644.360.024.319
D12.776.157.057.124
D12.776.476.024.402
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050828
Scope note: A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; PROTEIN INHIBITORS OF ACTIVATED STAT was indexed under PROTEINS 1998-2005
History Note: 2006(1998)
DeCS ID: 50781
Unique ID: D050828
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/03/30
Protein Inhibitors of Activated STAT - Preferred
Concept UI M0478067
Scope note A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Preferred term Protein Inhibitors of Activated STAT
Entry term(s) PIAS Proteins
PIAS2 Protein Inhibitor of Activated STAT - Narrower
Concept UI M0479990
Preferred term PIAS2 Protein Inhibitor of Activated STAT
PIAS4 Protein Inhibitor of Activated STAT - Narrower
Concept UI M0479993
Preferred term PIAS4 Protein Inhibitor of Activated STAT
PIAS3 Protein Inhibitor of Activated STAT - Narrower
Concept UI M0479991
Preferred term PIAS3 Protein Inhibitor of Activated STAT
PIAS1 Protein Inhibitor of Activated STAT - Narrower
Concept UI M0479986
Preferred term PIAS1 Protein Inhibitor of Activated STAT
Entry term(s) PIAS1 Protein



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