| Descriptor English: | Pyruvate Dehydrogenase Acetyl-Transferring Kinase | ||||||
| Descriptor Spanish: |
Piruvato Deshidrogenasa Quinasa Acetil-Transferidora
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| Descriptor Portuguese: | Piruvato Desidrogenase Quinase de Transferência de Acetil | ||||||
| Descriptor French: | Pyruvate dehydrogenase acetyl-transferring kinase | ||||||
| Entry term(s): |
Dehydrogenase Kinase, Pyruvate Kinase, PDH Kinase, Pyruvate Dehydrogenase PDH Kinase Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase Pyruvate Dehydrogenase (Lipoamide) Kinase Pyruvate Dehydrogenase Acetyl Transferring Kinase Pyruvate Dehydrogenase Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.700.783 D12.776.476.563.783 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000081382 | ||||||
| Scope note: | A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2021; see PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE 2020; was indexed under PROTEIN SERINE THREONINE KINASES 1972-2019 |
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| History Note: | 2021(1972) |
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| DeCS ID: | 59212 | ||||||
| Unique ID: | D000081382 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2020/01/01 | ||||||
| Date of Entry: | 2019/07/08 | ||||||
| Revision Date: | 2020/01/28 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Pyruvate Dehydrogenase Acetyl-Transferring Kinase
- Preferred
| Concept UI |
M000650517 |
| Scope note | A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism. |
| Preferred term | Pyruvate Dehydrogenase Acetyl-Transferring Kinase |
| Entry term(s) |
Dehydrogenase Kinase, Pyruvate Kinase, PDH Kinase, Pyruvate Dehydrogenase PDH Kinase Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase Pyruvate Dehydrogenase (Lipoamide) Kinase Pyruvate Dehydrogenase Acetyl Transferring Kinase Pyruvate Dehydrogenase Kinase |
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