| Descriptor English: | AMP-Activated Protein Kinases | ||||||
| Descriptor Spanish: |
Proteínas Quinasas Activadas por AMP
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| Descriptor Portuguese: | Proteínas Quinases Ativadas por AMP | ||||||
| Descriptor French: | AMP-Activated Protein Kinases | ||||||
| Entry term(s): |
5' AMP Activated Protein Kinase 5'-AMP-Activated Protein Kinase AMP Activated Kinase AMP Activated Protein Kinase AMP Activated Protein Kinase alpha Subunit AMP Activated Protein Kinase alpha Subunits AMP Activated Protein Kinase beta Subunit AMP Activated Protein Kinase beta Subunits AMP Activated Protein Kinase gamma Subunit AMP Activated Protein Kinase gamma Subunits AMP Activated Protein Kinases AMP-Activated Kinase AMP-Activated Protein Kinase AMP-Activated Protein Kinase alpha Subunit AMP-Activated Protein Kinase alpha Subunits AMP-Activated Protein Kinase beta Subunit AMP-Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase gamma Subunit AMP-Activated Protein Kinase gamma Subunits PRKAA |
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| Tree number(s): |
D08.811.913.696.620.682.700.085 D12.776.476.563.085 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D055372 | ||||||
| Scope note: | Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.31 | ||||||
| Public MeSH Note: | 2009; AMP-ACTIVATED PROTEIN KINASES was indexed under MULTIENZYME COMPLEXES & PROTEIN-SERINE-THREONIN KINASES 2000-2008, & under HMG COA REDUCTASES & PROTEIN KINASES 1980-2000 |
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| History Note: | 2009(1980) |
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| DeCS ID: | 53121 | ||||||
| Unique ID: | D055372 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2009/01/01 | ||||||
| Date of Entry: | 2008/07/08 | ||||||
| Revision Date: | 2017/02/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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AMP-Activated Protein Kinases
- Preferred
AMP-Activated Protein Kinase beta Subunits
- Narrower
AMP-Activated Protein Kinase gamma Subunits
- Narrower
AMP-Activated Protein Kinase alpha Subunits
- Narrower
| Concept UI |
M0517349 |
| Scope note | Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP. |
| Preferred term | AMP-Activated Protein Kinases |
| Entry term(s) |
5' AMP Activated Protein Kinase 5'-AMP-Activated Protein Kinase AMP Activated Kinase AMP Activated Protein Kinase AMP Activated Protein Kinases AMP-Activated Kinase AMP-Activated Protein Kinase |
| Concept UI |
M0290656 |
| Preferred term | AMP-Activated Protein Kinase beta Subunits |
| Entry term(s) |
AMP Activated Protein Kinase beta Subunit AMP Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase beta Subunit |
| Concept UI |
M0518043 |
| Preferred term | AMP-Activated Protein Kinase gamma Subunits |
| Entry term(s) |
AMP Activated Protein Kinase gamma Subunit AMP Activated Protein Kinase gamma Subunits AMP-Activated Protein Kinase gamma Subunit |
| Concept UI |
M0513385 |
| Preferred term | AMP-Activated Protein Kinase alpha Subunits |
| Entry term(s) |
AMP Activated Protein Kinase alpha Subunit AMP Activated Protein Kinase alpha Subunits AMP-Activated Protein Kinase alpha Subunit PRKAA |
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