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Descriptor English: Aurora Kinases
Descriptor Spanish: Aurora Quinasas
Descriptor aurora cinasas
Entry term(s) aurora quinasas
cinasa Aurora
Scope note: Familia de serina-treonina cinasas implicadas en la regulación de la MITOSIS. Intervienen en muchos aspectos de la división celular como la duplicación del centrosoma, la formación del HUSO ACROMÁTICO, el alineamiento de los cromosomas, su unión al huso, la activación regulada ("checkpoint activation") y la CITOCINESIS.
Descriptor Portuguese: Aurora Quinases
Descriptor French: Aurora kinases
Entry term(s): Aurora Kinase
Kinase, Aurora
Tree number(s): D08.811.913.696.620.682.700.103
D12.776.167.049
D12.776.476.563.103
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064127
Scope note: A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell division, including centrosome duplication, SPINDLE APPARATUS formation, chromosome alignment, attachment to the spindle, checkpoint activation, and CYTOKINESIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.1
Public MeSH Note: 2014; was indexed under PROTEIN-SERINE-THREONINE KINASES 1995-2013
History Note: 2014
DeCS ID: 55300
Unique ID: D064127
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2020/05/27
Aurora Kinases - Preferred
Concept UI M0579730
Scope note A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell division, including centrosome duplication, SPINDLE APPARATUS formation, chromosome alignment, attachment to the spindle, checkpoint activation, and CYTOKINESIS.
Preferred term Aurora Kinases
Entry term(s) Aurora Kinase
Kinase, Aurora



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