| Descriptor English: | 3-Phosphoinositide-Dependent Protein Kinases | ||||||
| Descriptor Spanish: |
Proteínas Quinasas Dependientes de 3-Fosfoinosítido
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| Descriptor Portuguese: | Proteínas Quinases Dependentes de 3-Fosfoinositídeo | ||||||
| Descriptor French: | 3-Phosphoinositide-dependent protein kinases | ||||||
| Entry term(s): |
3 Phosphoinositide Dependent Protein Kinase 3 Phosphoinositide Dependent Protein Kinase 1 3 Phosphoinositide Dependent Protein Kinase 2 3 Phosphoinositide Dependent Protein Kinases 3-Phosphoinositide Dependent Protein Kinase-1 3-Phosphoinositide Dependent Protein Kinase-2 3-Phosphoinositide-Dependent Kinase 1 (PDK1) 3-Phosphoinositide-Dependent Protein Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 3-Phosphoinositide-Dependent Protein Kinase-2 Kinase, 3-Phosphoinositide-Dependent Protein Kinase-1, 3-Phosphoinositide-Dependent Protein Kinase-2, 3-Phosphoinositide-Dependent Protein Kinases, 3-Phosphoinositide-Dependent Protein Protein Kinase, 3-Phosphoinositide-Dependent Protein Kinase-1, 3-Phosphoinositide-Dependent Protein Kinase-2, 3-Phosphoinositide-Dependent Protein Kinases, 3-Phosphoinositide-Dependent PtdIns(3,4,5)P3-Dependent Protein Kinase-1 |
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| Tree number(s): |
D08.811.913.696.620.682.700.745 D12.776.476.563.745 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064413 | ||||||
| Scope note: | Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3). |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Previous Indexing: |
Protein-Serine-Threonine Kinases (1997-2013) |
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| Public MeSH Note: | 2014; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1997-2013 |
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| History Note: | 2014 |
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| DeCS ID: | 55307 | ||||||
| Unique ID: | D064413 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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3-Phosphoinositide-Dependent Protein Kinases
- Preferred
3-Phosphoinositide Dependent Protein Kinase-1
- Narrower
3-Phosphoinositide Dependent Protein Kinase-2
- Narrower
| Concept UI |
M0581691 |
| Scope note | Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3). |
| Preferred term | 3-Phosphoinositide-Dependent Protein Kinases |
| Entry term(s) |
3 Phosphoinositide Dependent Protein Kinase 3 Phosphoinositide Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinase Kinase, 3-Phosphoinositide-Dependent Protein Kinases, 3-Phosphoinositide-Dependent Protein Protein Kinase, 3-Phosphoinositide-Dependent Protein Kinases, 3-Phosphoinositide-Dependent |
| Concept UI |
M0355177 |
| Preferred term | 3-Phosphoinositide Dependent Protein Kinase-1 |
| Entry term(s) |
3 Phosphoinositide Dependent Protein Kinase 1 3-Phosphoinositide-Dependent Kinase 1 (PDK1) 3-Phosphoinositide-Dependent Protein Kinase-1 Kinase-1, 3-Phosphoinositide-Dependent Protein Protein Kinase-1, 3-Phosphoinositide-Dependent PtdIns(3,4,5)P3-Dependent Protein Kinase-1 |
| Concept UI |
M0361155 |
| Preferred term | 3-Phosphoinositide Dependent Protein Kinase-2 |
| Entry term(s) |
3 Phosphoinositide Dependent Protein Kinase 2 3-Phosphoinositide-Dependent Protein Kinase-2 Kinase-2, 3-Phosphoinositide-Dependent Protein Protein Kinase-2, 3-Phosphoinositide-Dependent |
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