| Descriptor English: | Checkpoint Kinase 2 | ||||||
| Descriptor Spanish: |
Quinasa de Punto de Control 2
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| Descriptor Portuguese: | Quinase do Ponto de Checagem 2 | ||||||
| Descriptor French: | Checkpoint kinase 2 | ||||||
| Entry term(s): |
CDS1 Kinase CHEK2 Kinase CHK2, Checkpoint-Like Protein CHK2, Serine-Threonine-Protein Kinase Checkpoint Like Protein CHK2 Checkpoint-Like Protein CHK2 Chk2 Protein Kinase Kinase 2, Checkpoint Kinase CHK2, Serine-Threonine-Protein Kinase, CDS1 Kinase, CHEK2 Kinase, Chk2 Protein Kinase, LFS2 Protein Kinase, PP1425 Protein Kinase, hCHK2 LFS2 Protein Kinase PP1425 Protein Kinase Protein CHK2, Checkpoint-Like Protein Kinase, Chk2 Protein Kinase, LFS2 Protein Kinase, PP1425 Serine Threonine Protein Kinase Chk2 Serine-Threonine-Protein Kinase CHK2 hCHK2 Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.700.145 D12.776.476.563.145 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064447 | ||||||
| Scope note: | Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1. In humans it is encoded by the CHEK2 gene. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.1.11 | ||||||
| Public MeSH Note: | 2014; was indexed under PROTEIN-SERINE-THREONINE-KINASES 1995-2013. |
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| History Note: | 2014 |
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| DeCS ID: | 55305 | ||||||
| Unique ID: | D064447 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 | ||||||
| Revision Date: | 2016/06/28 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Checkpoint Kinase 2
- Preferred
| Concept UI |
M0245645 |
| Scope note | Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1. In humans it is encoded by the CHEK2 gene. |
| Preferred term | Checkpoint Kinase 2 |
| Entry term(s) |
CDS1 Kinase CHEK2 Kinase CHK2, Checkpoint-Like Protein CHK2, Serine-Threonine-Protein Kinase Checkpoint Like Protein CHK2 Checkpoint-Like Protein CHK2 Chk2 Protein Kinase Kinase 2, Checkpoint Kinase CHK2, Serine-Threonine-Protein Kinase, CDS1 Kinase, CHEK2 Kinase, Chk2 Protein Kinase, LFS2 Protein Kinase, PP1425 Protein Kinase, hCHK2 LFS2 Protein Kinase PP1425 Protein Kinase Protein CHK2, Checkpoint-Like Protein Kinase, Chk2 Protein Kinase, LFS2 Protein Kinase, PP1425 Serine Threonine Protein Kinase Chk2 Serine-Threonine-Protein Kinase CHK2 hCHK2 Kinase |
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