DeCS

Descriptor English:

Interleukin-1 Receptor-Associated Kinases

Descriptor Spanish:

Quinasas Asociadas a Receptores de Interleucina-1

Spanish from Spain

Descriptor	cinasas asociadas a receptores de interleucina-1
Scope note:	Familia de cinasas de señalización intracelular que fueron identificadas por su capacidad para señalar a partir de los RECEPTORES DE INTERLEUCINA-1 activados. La señalización originada en estas cinasas implica su interacción con las PROTEÍNAS ADAPTADORAS DE TRANSDUCCIÓN DE SEÑAL tales como el FACTOR 88 DE DIFERENCIACIÓN MIELOIDE y el FACTOR 6 ASOCIADO AL RECEPTOR DE TNF.

Descriptor Portuguese:

Quinases Associadas a Receptores de Interleucina-1

Descriptor French:

Interleukin-1 Receptor-Associated Kinases

Entry term(s):

IL 1 Receptor Associated Kinase
IL-1 Receptor-Associated Kinase
IRAK 1 Kinase
IRAK 2 Kinase
IRAK 3 Kinase
IRAK 4 Kinase
IRAK Kinases
IRAK-1 Kinase
IRAK-2 Kinase
IRAK-3 Kinase
IRAK-4 Kinase
Interleukin 1 Receptor Associated Kinase
Interleukin 1 Receptor Associated Kinase 1
Interleukin 1 Receptor Associated Kinase 2
Interleukin 1 Receptor Associated Kinase 3
Interleukin 1 Receptor Associated Kinase 4
Interleukin 1 Receptor Associated Kinases
Interleukin-1 Receptor-Associated Kinase
Interleukin-1 Receptor-Associated Kinase 1
Interleukin-1 Receptor-Associated Kinase 2
Interleukin-1 Receptor-Associated Kinase 3
Interleukin-1 Receptor-Associated Kinase 4
Kinase, IL-1 Receptor-Associated
Kinase, IRAK-1
Kinase, IRAK-2
Kinase, IRAK-3
Kinase, IRAK-4
Kinase, Interleukin-1 Receptor-Associated
Kinases, IRAK
Kinases, Interleukin-1 Receptor-Associated
Receptor-Associated Kinase, IL-1
Receptor-Associated Kinase, Interleukin-1
Receptor-Associated Kinases, Interleukin-1

Tree number(s):

D08.811.913.696.620.682.700.526
D12.776.476.563.526

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D053592

Scope note:

A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Registry Number:

EC 2.7.11.1

Public MeSH Note:

2007; INTERLEUKIN-1 RECEPTOR-ASSCIATED KINASES was indexed under PROTEIN-SERINE-THREONINE KINASES & INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 2006, & under PROTEIN KINASES 1996-2006

Concept UI	M0258081
Scope note	A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
Preferred term	Interleukin-1 Receptor-Associated Kinases
Entry term(s)	IL 1 Receptor Associated Kinase IL-1 Receptor-Associated Kinase IRAK Kinases Interleukin 1 Receptor Associated Kinase Interleukin 1 Receptor Associated Kinases Interleukin-1 Receptor-Associated Kinase Kinase, IL-1 Receptor-Associated Kinase, Interleukin-1 Receptor-Associated Kinases, IRAK Kinases, Interleukin-1 Receptor-Associated Receptor-Associated Kinase, IL-1 Receptor-Associated Kinase, Interleukin-1 Receptor-Associated Kinases, Interleukin-1

Concept UI	M0494876
Preferred term	Interleukin-1 Receptor-Associated Kinase 4
Entry term(s)	IRAK 4 Kinase IRAK-4 Kinase Interleukin 1 Receptor Associated Kinase 4 Kinase, IRAK-4

Concept UI	M0494874
Preferred term	Interleukin-1 Receptor-Associated Kinase 3
Entry term(s)	IRAK 3 Kinase IRAK-3 Kinase Interleukin 1 Receptor Associated Kinase 3 Kinase, IRAK-3

Concept UI	M0494872
Preferred term	Interleukin-1 Receptor-Associated Kinase 1
Entry term(s)	IRAK 1 Kinase IRAK-1 Kinase Interleukin 1 Receptor Associated Kinase 1 Kinase, IRAK-1

Concept UI	M0258080
Preferred term	Interleukin-1 Receptor-Associated Kinase 2
Entry term(s)	IRAK 2 Kinase IRAK-2 Kinase Interleukin 1 Receptor Associated Kinase 2 Kinase, IRAK-2

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