| Descriptor English: | Proto-Oncogene Proteins c-akt | ||||||
| Descriptor Spanish: |
Proteínas Proto-Oncogénicas c-akt
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| Descriptor Portuguese: | Proteínas Proto-Oncogênicas c-akt | ||||||
| Descriptor French: | Protéines proto-oncogènes c-akt | ||||||
| Entry term(s): |
AKT1 Protein Kinase AKT2 Protein Kinase AKT3 Protein Kinase Akt alpha Protein Akt beta Protein Akt gamma Protein Akt, Proto-Oncogene Protein Akt-alpha Protein Akt-beta Protein Akt-gamma Protein Protein Kinase B Protein Kinase B alpha Protein Kinase B beta Protein Kinase B gamma Protein, akt Proto-Oncogene Protein, c-akt Proto-Oncogene Protein-Serine-Threonine Kinase (Rac) Proteins c-akt1, Proto-Oncogene Proteins c-akt2, Proto-Oncogene Proteins c-akt3, Proto-Oncogene Proto Oncogene Protein Akt Proto Oncogene Protein RAC Proto Oncogene Proteins c akt Proto Oncogene Proteins c akt1 Proto Oncogene Proteins c akt2 Proto Oncogene Proteins c akt3 Proto-Oncogene Protein Akt Proto-Oncogene Protein RAC Proto-Oncogene Protein, akt Proto-Oncogene Protein, c-akt Proto-Oncogene Proteins c-akt1 Proto-Oncogene Proteins c-akt2 Proto-Oncogene Proteins c-akt3 RAC PK Protein RAC, Proto-Oncogene Protein RAC-PK Protein Rac PK alpha Protein Rac PK beta Protein Rac Protein Kinase Rac-PK alpha Protein Rac-PK beta Protein Related to A and C Protein Related to A and C-Protein akt Proto Oncogene Protein akt Proto-Oncogene Protein alpha Protein, Rac-PK c akt Proto Oncogene Protein c-akt Protein c-akt Proto-Oncogene Protein c-akt, Proto-Oncogene Proteins c-akt1, Proto-Oncogene Proteins c-akt2, Proto-Oncogene Proteins c-akt3, Proto-Oncogene Proteins |
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| Tree number(s): |
D08.811.913.696.620.682.700.755 D12.776.476.563.755 D12.776.624.664.700.168 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051057 | ||||||
| Scope note: | Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Public MeSH Note: | 2006; PROTO-ONCOGENE PROTEINS C-AKT was indexed under PROTEIN-SERINE-THREONINE KINASES & PROTO-ONCOGENE PROTEINS 1987-2005 |
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| History Note: | 2006(1987) |
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| DeCS ID: | 50724 | ||||||
| Unique ID: | D051057 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Proto-Oncogene Proteins c-akt
- Preferred
Proto-Oncogene Proteins c-akt1
- Narrower
Proto-Oncogene Proteins c-akt2
- Narrower
Proto-Oncogene Proteins c-akt3
- Narrower
| Concept UI |
M0150739 |
| Scope note | Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells. |
| Preferred term | Proto-Oncogene Proteins c-akt |
| Entry term(s) |
Akt, Proto-Oncogene Protein Protein Kinase B Protein, akt Proto-Oncogene Protein, c-akt Proto-Oncogene Protein-Serine-Threonine Kinase (Rac) Proto Oncogene Protein Akt Proto Oncogene Protein RAC Proto Oncogene Proteins c akt Proto-Oncogene Protein Akt Proto-Oncogene Protein RAC Proto-Oncogene Protein, akt Proto-Oncogene Protein, c-akt RAC PK Protein RAC, Proto-Oncogene Protein RAC-PK Protein Rac Protein Kinase Related to A and C Protein Related to A and C-Protein akt Proto Oncogene Protein akt Proto-Oncogene Protein c akt Proto Oncogene Protein c-akt Protein c-akt Proto-Oncogene Protein c-akt, Proto-Oncogene Proteins |
| Concept UI |
M0283975 |
| Preferred term | Proto-Oncogene Proteins c-akt1 |
| Entry term(s) |
AKT1 Protein Kinase Akt alpha Protein Akt-alpha Protein Protein Kinase B alpha Proteins c-akt1, Proto-Oncogene Proto Oncogene Proteins c akt1 Rac PK alpha Protein Rac-PK alpha Protein alpha Protein, Rac-PK c-akt1, Proto-Oncogene Proteins |
| Concept UI |
M0479108 |
| Preferred term | Proto-Oncogene Proteins c-akt2 |
| Entry term(s) |
AKT2 Protein Kinase Akt beta Protein Akt-beta Protein Protein Kinase B beta Proteins c-akt2, Proto-Oncogene Proto Oncogene Proteins c akt2 Rac PK beta Protein Rac-PK beta Protein c-akt2, Proto-Oncogene Proteins |
| Concept UI |
M0479107 |
| Preferred term | Proto-Oncogene Proteins c-akt3 |
| Entry term(s) |
AKT3 Protein Kinase Akt gamma Protein Akt-gamma Protein Protein Kinase B gamma Proteins c-akt3, Proto-Oncogene Proto Oncogene Proteins c akt3 c-akt3, Proto-Oncogene Proteins |
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