| Descriptor English: | Positive Transcriptional Elongation Factor B | ||||||
| Descriptor Spanish: |
Factor B de Elongación Transcripcional Positiva
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| Descriptor Portuguese: | Fator B de Elongação Transcricional Positiva | ||||||
| Descriptor French: | Facteur B d'élongation transcriptionnelle positive | ||||||
| Entry term(s): |
P-TEFb Positive Transcription Elongation Factor B tat Associated Kinase tat-Associated Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.700.626 D12.776.476.563.626 D12.776.930.955.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D042925 | ||||||
| Scope note: | A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.- | ||||||
| Previous Indexing: |
Protein-Serine-Threonine Kinases (1996-2003) |
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| Public MeSH Note: | 2004; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B was indexed under PROTEIN-SERINE-THREONINE KINASES 1996-2003 |
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| History Note: | 2004; use POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B (NM) 1996-2003 |
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| DeCS ID: | 38314 | ||||||
| Unique ID: | D042925 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Positive Transcriptional Elongation Factor B
- Preferred
| Concept UI |
M0265832 |
| Scope note | A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II. |
| Preferred term | Positive Transcriptional Elongation Factor B |
| Entry term(s) |
P-TEFb Positive Transcription Elongation Factor B tat Associated Kinase tat-Associated Kinase |
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