| Descriptor English: | TOR Serine-Threonine Kinases | ||||||
| Descriptor Spanish: |
Serina-Treonina Quinasas TOR
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| Descriptor Portuguese: | Serina-Treonina Quinases TOR | ||||||
| Descriptor French: | Sérine-thréonine kinases TOR | ||||||
| Entry term(s): |
FK506 Binding Protein 12 Rapamycin Associated Protein 1 FK506 Binding Protein 12-Rapamycin Associated Protein 1 FKBP12 Rapamycin Associated Protein FKBP12 Rapamycin Complex Associated Protein FKBP12-Rapamycin Associated Protein FKBP12-Rapamycin Complex-Associated Protein Kinase, TOR Kinase, TOR Serine-Threonine Kinase, mTOR Serine-Threonine Kinases, TOR Serine-Threonine Kinases, mTOR Serine-Threonine Mammalian Target of Rapamycin Mechanistic Target of Rapamycin Protein Protein Target, Rapamycin Protein, RAFT-1 Protein, mTOR RAFT 1 Protein RAFT-1 Protein Rapamycin Protein Target Rapamycin Target Protein Serine-Threonine Kinase, TOR Serine-Threonine Kinase, mTOR Serine-Threonine Kinases, TOR Serine-Threonine Kinases, mTOR TOR Kinase TOR Kinases TOR Serine Threonine Kinase TOR Serine Threonine Kinases TOR Serine-Threonine Kinase Target of Rapamycin Protein Target of Rapamycin Proteins mTOR Protein mTOR Serine Threonine Kinase mTOR Serine Threonine Kinases mTOR Serine-Threonine Kinase mTOR Serine-Threonine Kinases |
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| Tree number(s): |
D08.811.913.696.620.682.700.931 D12.776.476.563.931 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D058570 | ||||||
| Scope note: | A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.1.1 | ||||||
| Public MeSH Note: | 2011; MTOR PROTEIN (now TOR SERINE-THREONINE KINASES) was indexed under PROTEIN KINASES 1995-2010 and under PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR) 1995-2001 |
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| History Note: | 2011 |
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| DeCS ID: | 54051 | ||||||
| Unique ID: | D058570 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2011/01/01 | ||||||
| Date of Entry: | 2010/06/25 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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TOR Serine-Threonine Kinases
- Preferred
| Concept UI |
M0543256 |
| Scope note | A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity. |
| Preferred term | TOR Serine-Threonine Kinases |
| Entry term(s) |
FK506 Binding Protein 12 Rapamycin Associated Protein 1 FK506 Binding Protein 12-Rapamycin Associated Protein 1 FKBP12 Rapamycin Associated Protein FKBP12 Rapamycin Complex Associated Protein FKBP12-Rapamycin Associated Protein FKBP12-Rapamycin Complex-Associated Protein Kinase, TOR Kinase, TOR Serine-Threonine Kinase, mTOR Serine-Threonine Kinases, TOR Serine-Threonine Kinases, mTOR Serine-Threonine Mammalian Target of Rapamycin Mechanistic Target of Rapamycin Protein Protein Target, Rapamycin Protein, RAFT-1 Protein, mTOR RAFT 1 Protein RAFT-1 Protein Rapamycin Protein Target Rapamycin Target Protein Serine-Threonine Kinase, TOR Serine-Threonine Kinase, mTOR Serine-Threonine Kinases, TOR Serine-Threonine Kinases, mTOR TOR Kinase TOR Kinases TOR Serine Threonine Kinase TOR Serine Threonine Kinases TOR Serine-Threonine Kinase Target of Rapamycin Protein Target of Rapamycin Proteins mTOR Protein mTOR Serine Threonine Kinase mTOR Serine Threonine Kinases mTOR Serine-Threonine Kinase mTOR Serine-Threonine Kinases |
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