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Descriptor English: OX40 Ligand
Descriptor Spanish: Ligando OX40
Descriptor ligando OX40
Entry term(s) miembro 4 de la superfamilia de ligandos del factor de necrosis tumoral
Scope note: Miembro de la familia de necrosis tumoral unido a la membrana que se expresda en las células presentadoras de antígeno activadas tales como los LINFOCITOS B y los MACRÓFAGOS. Señaliza a los LINFOCITOS T al unirse al RECEPTOR OX40.
Descriptor Portuguese: Ligante OX40
Descriptor French: Ligand de OX40
Entry term(s): CD134 Ligand
CD134L Protein
OX40L Protein
TNF Superfamily, Member 4
Tumor Necrosis Factor (Ligand) Superfamily, Member 4
Tumor Necrosis Factor Ligand Superfamily Member 4
gp34 Tumor Necrosis Factor
Tree number(s): D12.644.276.374.750.531
D12.776.395.550.597
D12.776.465.813
D12.776.467.374.750.531
D12.776.543.550.590
D23.529.374.750.531
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053278
Scope note: A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Membrane Glycoproteins (2002-2005)
Receptors, Tumor Necrosis Factor (1994-2001)
Tumor Necrosis Factors (2006)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52296
Unique ID: D053278
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/06/23
OX40 Ligand - Preferred
Concept UI M0492257
Scope note A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR.
Preferred term OX40 Ligand
Entry term(s) CD134 Ligand
CD134L Protein
OX40L Protein
TNF Superfamily, Member 4
Tumor Necrosis Factor (Ligand) Superfamily, Member 4
Tumor Necrosis Factor Ligand Superfamily Member 4
gp34 Tumor Necrosis Factor



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