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Descriptor English: SMARCB1 Protein
Descriptor Spanish: Proteína SMARCB1
Descriptor proteína SMARCB1
Entry term(s) Proteína BAF47
factor asociado a BRG1 47
factor proteico asociado a BRG1
miembro 1 de la subfamilia B regulador de la cromatina dependiente de actina asociado a la matriz y relacionado con Swi-Snf
proteína del factor 47 asociado a BRG1
proteína homóloga a SNF5
proteína integrasa interactor 1
proteína integrasa interactora 1
regulador de la cromatina dependiente de actina asociado a la matriz y relacionado con Swi-Snf, subfamilia B, miembro 1
Scope note: Componente del COMPLEJO REMODELADOR DE LA CROMATINA SWI-SNF que regula la PROTEÍNA FOSFATASA 1 y estabiliza la CROMATINA en las REGIONES PROMOTORAS. Es importante para regular la PROLIFERACIÓN CELULAR y la DIFERENCIACIÓN CELULAR. Las mutaciones en el gen SMARCB1 se asocian a TUMORES RABDOIDES malignos.
Descriptor Portuguese: Proteína SMARCB1
Descriptor French: Protéine SMARCB1
Entry term(s): BAF47 Protein
BRG1 Associated Factor 47 Protein
BRG1-Associated Factor 47 Protein
Integrase Interactor 1 Protein
SNF5 Homolog Protein
Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1
Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1
Tree number(s): D12.776.260.716
D12.776.660.235.650
D12.776.664.235.900
D12.776.930.809
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071796
Scope note: A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Chromosomal Proteins, Non-Histone (2006-2016)
DNA-Binding Proteins (2006-2016)
Transcription Factors (2006-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56609
Unique ID: D000071796
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/28
SMARCB1 Protein - Preferred
Concept UI M000615545
Scope note A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.
Preferred term SMARCB1 Protein
Entry term(s) BAF47 Protein
BRG1 Associated Factor 47 Protein
BRG1-Associated Factor 47 Protein
Integrase Interactor 1 Protein
SNF5 Homolog Protein
Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1
Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1



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