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Descriptor English: Methyl-CpG-Binding Protein 2
Descriptor Spanish: Proteína 2 de Unión a Metil-CpG
Descriptor proteína 2 de unión a metil-CpG
Scope note: Proteína de unión al ADN que interacciona con ISLAS CPG metiladas. Interviene en la represión de la TRANSCRIPCIÓN y frecuentemente está mutada en el SÍNDROME DE RETT.
Descriptor Portuguese: Proteína 2 de Ligação a Metil-CpG
Descriptor French: Protéine-2 de liaison au CpG méthylé
Entry term(s): MeCP2 Protein
Methyl CpG Binding Protein 2
Tree number(s): D12.776.260.536
D12.776.660.235.550
D12.776.664.235.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051783
Scope note: A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENETIC TRANSCRIPTION and is frequently mutated in RETT SYNDROME.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; METHYL-CPG-BINDING PROTEIN 2 was indexed under CHROMOSOMAL PROTEINS, NON-HISTONE & DNA-BINDING PROTEINS & REPRESSOR PROTEINS 2005, & under TRANSCRIPTION FACTORS 1992-2004
History Note: 2006(1992)
Related: Methyl CpG Binding Domain MeSH
Rett Syndrome MeSH
DeCS ID: 51019
Unique ID: D051783
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/24
Methyl-CpG-Binding Protein 2 - Preferred
Concept UI M0208047
Scope note A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENETIC TRANSCRIPTION and is frequently mutated in RETT SYNDROME.
Preferred term Methyl-CpG-Binding Protein 2
Entry term(s) MeCP2 Protein
Methyl CpG Binding Protein 2



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