| Descriptor English: | Receptor, ErbB-3 | ||||||
| Descriptor Spanish: |
Receptor ErbB-3
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| Descriptor Portuguese: | Receptor ErbB-3 | ||||||
| Descriptor French: | Récepteur ErbB-3 | ||||||
| Entry term(s): |
ErbB-3 Receptor HER 3 Proto Oncogene Protein HER-3 Proto-Oncogene Protein Protein c-ErbB-2, Proto-oncogene-like Proto Oncogene Protein c erbB 3 Proto Oncogene Protein erbB 3 Proto Oncogene Proteins erbB 3 Proto oncogene like Protein c ErbB 2 Proto-Oncogene Protein c-erbB-3 Proto-Oncogene Protein erbB-3 Proto-Oncogene Protein, HER-3 Proto-Oncogene Proteins erbB-3 Proto-oncogene-like Protein c-ErbB-2 Receptor, ErbB 3 Tyrosine Kinase type Cell Surface Receptor HER3 Tyrosine Kinase-type Cell Surface Receptor HER3 c erbB 3 Protein c-ErbB-2, Proto-oncogene-like Protein c-erbB-3 Protein c-erbB-3, Proto-Oncogene Protein erbB 3 Protein erbB-3 Protein erbB-3, Proto-Oncogene Protein erbB-3, Proto-Oncogene Proteins |
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| Tree number(s): |
D08.811.913.696.620.682.725.400.009.500 D12.776.476.568.400.009.500 D12.776.543.750.630.009.500 D12.776.543.750.750.400.074.500 D12.776.624.664.700.790 D23.101.140.721 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020893 | ||||||
| Scope note: | A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF RECEPTOR and the ERBB-2 RECEPTOR. Overexpression of the erbB-3 receptor is associated with TUMORIGENESIS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.10.1 | ||||||
| Previous Indexing: |
Proto-Oncogene Proteins (1993-1999) Receptor, Epidermal Growth Factor (1990-1999) |
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| Public MeSH Note: | 2000; PROTO-ONCOGENE PROTEIN ERBB-3 (now RECEPTOR, ERBB-3) was indexed under EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE 1993-1999 & PROTO-ONCOGENE PROTEINS 1990-1999 |
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| History Note: | 2000; use RECEPTOR, ERBB-3 (NM) 1990-1999 |
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| Related: |
Arthrogryposis
MeSH Genes, erbB MeSH | ||||||
| DeCS ID: | 34452 | ||||||
| Unique ID: | D020893 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2000/01/01 | ||||||
| Date of Entry: | 1999/11/03 | ||||||
| Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Receptor, ErbB-3
- Preferred
| Concept UI |
M0328262 |
| Scope note | A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF RECEPTOR and the ERBB-2 RECEPTOR. Overexpression of the erbB-3 receptor is associated with TUMORIGENESIS. |
| Preferred term | Receptor, ErbB-3 |
| Entry term(s) |
ErbB-3 Receptor HER 3 Proto Oncogene Protein HER-3 Proto-Oncogene Protein Protein c-ErbB-2, Proto-oncogene-like Proto Oncogene Protein c erbB 3 Proto Oncogene Protein erbB 3 Proto Oncogene Proteins erbB 3 Proto oncogene like Protein c ErbB 2 Proto-Oncogene Protein c-erbB-3 Proto-Oncogene Protein erbB-3 Proto-Oncogene Protein, HER-3 Proto-Oncogene Proteins erbB-3 Proto-oncogene-like Protein c-ErbB-2 Receptor, ErbB 3 Tyrosine Kinase type Cell Surface Receptor HER3 Tyrosine Kinase-type Cell Surface Receptor HER3 c erbB 3 Protein c-ErbB-2, Proto-oncogene-like Protein c-erbB-3 Protein c-erbB-3, Proto-Oncogene Protein erbB 3 Protein erbB-3 Protein erbB-3, Proto-Oncogene Protein erbB-3, Proto-Oncogene Proteins |
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